ACTG1 and NR3C2

Number of citations of the paper that reports this interaction (PubMedID 8612804)
2

Data Source:
HPRD (in vitro)

		ACTG1	NR3C2
Description		actin gamma 1	nuclear receptor subfamily 3 group C member 2
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GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Cytoskeleton Actin Filament Plasma Membrane Cell-cell Junction Focal Adhesion Membrane Myofibril Filamentous Actin Apical Junction Complex Calyx Of Held Phagocytic Vesicle Extracellular Exosome Blood Microparticle Dense Body Schaffer Collateral - CA1 Synapse	Nuclear Chromatin Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Receptor Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Profilin Binding ATP Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Structural Constituent Of Postsynaptic Actin Cytoskeleton	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Steroid Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Angiogenesis Morphogenesis Of A Polarized Epithelium Retina Homeostasis Positive Regulation Of Gene Expression Positive Regulation Of Cell Migration Cell Junction Assembly Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Sarcomere Organization Ephrin Receptor Signaling Pathway Synaptic Vesicle Endocytosis Regulation Of Stress Fiber Assembly Regulation Of Focal Adhesion Assembly Membrane Organization Platelet Aggregation Cellular Response To Interferon-gamma Positive Regulation Of Wound Healing Postsynaptic Actin Cytoskeleton Organization Tight Junction Assembly Protein Localization To Bicellular Tight Junction	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Steroid Hormone Mediated Signaling Pathway Positive Regulation Of NIK/NF-kappaB Signaling
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Gap junction degradation Formation of annular gap junctions Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling EPH-ephrin mediated repulsion of cells Adherens junctions interactions Adherens junctions interactions Recycling pathway of L1 Recycling pathway of L1 VEGFA-VEGFR2 Pathway Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins Cell-extracellular matrix interactions RHO GTPases activate IQGAPs RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate Formins RHO GTPases Activate Formins MAP2K and MAPK activation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Clathrin-mediated endocytosis Signaling downstream of RAS mutants FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	HSP90 chaperone cycle for steroid hormone receptors (SHR) SUMOylation of intracellular receptors
Drugs		Copper Artenimol	Nimodipine Progesterone Spironolactone Fluticasone propionate Testosterone Fludrocortisone Eplerenone Felodipine Desoxycorticosterone Pivalate Drospirenone Dihydrotestosterone Methyltrienolone Aldosterone Corticosterone
Diseases			Hyperkalemic distal renal tubular acidosis (RTA type 4), including the following two diseases: Pseudohypoaldosteronism type I (PHA1); Pseudohypoaldosteronism type II (Gordon's syndrome) Hypertension exacerbated in pregnancy
GWAS		Hand grip strength ( 29313844)	Alzheimer disease and age of onset ( 26830138) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Biochemical measures ( 19260141) Blond vs. brown/black hair color ( 30531825) Central corneal thickness ( 29760442) Corneal structure ( 23291589) Hippocampal volume ( 31530798) Hypothyroidism ( 27182965) Microalbuminuria ( 31511532) Plasma thyroid-stimulating hormone levels ( 28333968) Subcutaneous adipose tissue ( 22589738) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532) Vestibular neuritis ( 30079052)
Interacting Genes		65 interacting genes: ABLIM1 ACTB ANXA5 ATF7IP BCAP31 BIN1 BRCA1 CAP1 CAP2 CAPZA3 CCDC22 CDKN2A CFL1 CFL2 COTL1 CTBP2 CTTN CYBB DISC1 DNASE1 DSTN DYNLL1 EHHADH EIF6 FHOD1 FPR1 GIT2 GSN GZMA GZMK HRAS HSPB2 LGALS13 LIG4 LSP1 MAP1A MAPK6 MAPT MCPH1 MYO1A MYOC NDRG1 NR3C2 NTAQ1 PFN2 PLD1 PLEC PPP1R9A PRSS23 PSEN2 PTPRO RPS6KA5 SCIN SH3GL2 SRPK2 ST3GAL3 SUMO4 TMSB4X TMSB4Y TNIK VASP VIL1 WASF1 WASL WIPF1	20 interacting genes: ACSL1 ACTA1 ACTG1 AR CASP8AP2 FKBP4 HSP90AA1 HSPA4 NCOA1 NR3C1 PIAS1 PIAS3 PROX1 PSMC5 PTGES3 RABAC1 RXRA SUMO1 TRIM24 UBE2I
Entrez ID		71	4306
HPRD ID		00017	02991
Ensembl ID		ENSG00000184009	ENSG00000151623
Uniprot IDs		P63261	B0ZBF6 P08235
PDB IDs		5JLH 6CXI 6CXJ 6G2T	1Y9R 1YA3 2A3I 2AA2 2AA5 2AA6 2AA7 2AAX 2AB2 2ABI 2OAX 3VHU 3VHV 3WFF 3WFG 4PF3 4TNT 4UDA 4UDB 5HCV 5L7E 5L7G 5L7H 5MWP 5MWY 6GEV 6GG8 6GGG
Enriched GO Terms of Interacting Partners?
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