TGM2 and CERT1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		TGM2	CERT1
Description		transglutaminase 2	ceramide transporter 1
Image
GO Annotations	Cellular Component	Cell Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Focal Adhesion Intrinsic Component Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome	Nucleoplasm Mitochondrion Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding GTP Binding Protein Domain Specific Binding Identical Protein Binding Metal Ion Binding	Protein Binding Lipid Binding Kinase Activity Phosphatidylinositol-4-phosphate Binding Ceramide Binding Intermembrane Ceramide Transfer Activity Ceramide 1-phosphate Binding Ceramide 1-phosphate Transporter Activity
	Biological Process	Blood Vessel Remodeling Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Apoptotic Cell Clearance Positive Regulation Of Cell Adhesion Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Inflammatory Response Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Branching Involved In Salivary Gland Morphogenesis Salivary Gland Cavitation	Cell Morphogenesis In Utero Embryonic Development Heart Morphogenesis Ceramide Metabolic Process Muscle Contraction Immune Response Endoplasmic Reticulum Organization Signal Transduction Cell Proliferation Phosphorylation Sphingolipid Biosynthetic Process Response To Endoplasmic Reticulum Stress ER To Golgi Ceramide Transport Ceramide Transport Lipid Homeostasis Mitochondrion Morphogenesis Intermembrane Lipid Transfer Intermembrane Sphingolipid Transfer Ceramide 1-phosphate Transport
Pathways
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS
Interacting Genes		59 interacting genes: A2M ABCA1 ACTB ADAR ALDOA ANKRD28 ANXA1 APP ARNT ATF4 BNIP3 C3 CASP3 CBL CERT1 CSNK2A2 EIF5A FN1 FNTA GCGR GRN GSTP1 H2BC21 H2BC8 HNRNPF HNRNPUL1 HP HSPA1A HSPA1B HSPA8 HTT ITGB1 ITGB3 KPNA3 KPNA4 LACRT LTBP1 MAP3K12 PAK1 PINK1 PLCD1 PPHLN1 PXN RB1 RELA RHOA S100A7 SERPINF2 SERTAD1 SIPA1L2 SLC7A9 SMAD2 SMAD3 SPARC TAB2 TMEM176A TMSB4X TUBB ZNF512B	11 interacting genes: ACTL8 AQP2 ARL6IP1 CBS COL4A3 CSNK1G2 ITGB3BP POM121 RTN3 RTN4 TGM2
Entrez ID		7052	10087
HPRD ID		01825	05246
Ensembl ID		ENSG00000198959	ENSG00000113163
Uniprot IDs		B4DIT7 B4DTN7 P21980 V9HWG3	A0A024RAJ5 A0A2R8Y7C5 Q9Y5P4
PDB IDs		1FAU 1KV3 2Q3Z 3LY6 3S3J 3S3P 3S3S 4PYG 6A8P	2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2RSG 2Z9Y 2Z9Z 3H3Q 3H3R 3H3S 3H3T 4HHV 5JJD 5ZYG 5ZYH 5ZYI 5ZYJ 5ZYK 5ZYL 5ZYM 6IEZ 6IF0 6J0O 6J81
Enriched GO Terms of Interacting Partners?
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