TGFBR2 and TGFB2

  • Number of citations of the paper that reports this interaction (PubMedID 8106553)
  • 73
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

TGFBR2

TGFB2

Description transforming growth factor beta receptor 2 transforming growth factor beta 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181 30542056)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Bone mineral density (hip) ( 30172743)
  • Central corneal thickness ( 29760442)
  • Chronic obstructive pulmonary disease ( 28166215 30804561)
  • Chronic obstructive pulmonary disease (severe) ( 24621683)
  • Diastolic blood pressure ( 30224653)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Emphysema imaging phenotypes ( 26030696)
  • FEV1 ( 30804560)
  • Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
  • Heel bone mineral density ( 30598549)
  • Height ( 20881960 25282103 25429064 31562340)
  • Hip circumference adjusted for BMI ( 25673412)
  • Hip minimal joint space width ( 27701424)
  • Intraocular pressure ( 29617998)
  • Local histogram emphysema pattern ( 25006744)
  • Lung function (FEV1/FVC) ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Peak expiratory flow ( 30804560)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Pulmonary function ( 21946350)
  • Rosacea symptom severity ( 29771307)
  • Systolic blood pressure ( 30578418)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes 46 interacting genes: ACVR1 ACVRL1 AP2B1 APP ARHGEF6 ARHGEF7 CBL CCNB1 CCNB2 CD44 CDK1 CLU CTNNB1 DAB2 DAXX EIF3I ENG GOPC KCNK18 NRP1 OSR1 PAK1 PDGFRA PIK3R1 PIK3R2 PML PSMD14 RCVRN SMAD3 SMAD4 SMAD7 SNX6 STRAP TCTEX1D4 TDGF1 TERT TGFB1 TGFB1I1 TGFB2 TGFB3 TGFBR1 TGFBR3 TGFBRAP1 TRAP1 TSSK1B ZFYVE9 16 interacting genes: APP BMP2 CCN2 DCN ENG FMOD LTBP3 MARK1 PZP TGFB1 TGFB3 TGFBR1 TGFBR2 TGFBR3 VASN VTN
Entrez ID 7048 7042
HPRD ID 01823 01828
Ensembl ID ENSG00000163513 ENSG00000092969
Uniprot IDs A3QNQ0 D2JYI1 P37173 P61812 Q59EG9
PDB IDs 1KTZ 1M9Z 1PLO 2PJY 3KFD 4P7U 4XJJ 5E8V 5E8Y 5E91 5E92 5QIN 5TX4 5TY4 1TFG 2TGI 4KXZ 5TX4 5TY4 6I9J
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?