TGFB2 and TGFB1

  • Number of citations of the paper that reports this interaction (PubMedID 11157754)
  • 21
  • Data Source:
  • HPRD (in vivo)

TGFB2

TGFB1

Description transforming growth factor beta 2 transforming growth factor beta 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181 30542056)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Bone mineral density (hip) ( 30172743)
  • Central corneal thickness ( 29760442)
  • Chronic obstructive pulmonary disease ( 28166215 30804561)
  • Chronic obstructive pulmonary disease (severe) ( 24621683)
  • Diastolic blood pressure ( 30224653)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Emphysema imaging phenotypes ( 26030696)
  • FEV1 ( 30804560)
  • Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
  • Heel bone mineral density ( 30598549)
  • Height ( 20881960 25282103 25429064 31562340)
  • Hip circumference adjusted for BMI ( 25673412)
  • Hip minimal joint space width ( 27701424)
  • Intraocular pressure ( 29617998)
  • Local histogram emphysema pattern ( 25006744)
  • Lung function (FEV1/FVC) ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Peak expiratory flow ( 30804560)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Pulmonary function ( 21946350)
  • Rosacea symptom severity ( 29771307)
  • Systolic blood pressure ( 30578418)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412 28448500)
  • Blood protein levels ( 30072576)
  • Colorectal cancer ( 27145994 24836286)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Coronary artery disease ( 29212778 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Hematuria ( 30476138)
  • Hematuria (mild) ( 30476138)
  • Hematuria (moderate to severe) ( 30476138)
  • Preterm birth (maternal effect) ( 28877031)
  • Pulse pressure ( 30578418)
  • Type 2 diabetes ( 31049640)
Interacting Genes 16 interacting genes: APP BMP2 CCN2 DCN ENG FMOD LTBP3 MARK1 PZP TGFB1 TGFB3 TGFBR1 TGFBR2 TGFBR3 VASN VTN 59 interacting genes: ACVRL1 AGR3 ANGPTL4 APP BCAS3 BGN BLID BMP2 BMP3 CCDC33 CCL3 CCL5 CCN2 COL2A1 CST6 DAXX DCN DIRAS3 DPT EIF3I ENG FCN1 FKBP1A FMOD FNTA GREB1 HOXC6 ITGAV ITGB6 ITGB8 KLK5 KLK7 KLK9 LAMTOR5 LTBP1 LTBP3 LTBP4 MEOX2 MMP2 MTA3 NSD3 PDLIM2 PRSS50 PSMC3IP PZP SCGB3A1 SDC2 SNAI1 SPARC ST14 TGFB2 TGFBR1 TGFBR2 TGFBR3 THBS1 THRSP VASN VTN YWHAE
Entrez ID 7042 7040
HPRD ID 01828 01821
Ensembl ID ENSG00000092969 ENSG00000105329
Uniprot IDs P61812 Q59EG9 A0A499FJK2 P01137
PDB IDs 1TFG 2TGI 4KXZ 5TX4 5TY4 6I9J 1KLA 1KLC 1KLD 3KFD 4KV5 5FFO 5VQP
Enriched GO Terms of Interacting Partners?
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