TGFB1 and HOXC6

  • Number of citations of the paper that reports this interaction (PubMedID 25640309)
  • 5
  • Data Source:
  • BioGRID (two hybrid)

TGFB1

HOXC6

Description transforming growth factor beta 1 homeobox C6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Colorectal cancer ( 27145994 24836286)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Coronary artery disease ( 29212778 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Hematuria ( 30476138)
  • Hematuria (mild) ( 30476138)
  • Hematuria (moderate to severe) ( 30476138)
  • Preterm birth (maternal effect) ( 28877031)
  • Pulse pressure ( 30578418)
  • Type 2 diabetes ( 31049640)
  • Hippocampal volume ( 25625606)
  • Lumbar spine bone mineral density ( 22504420)
  • Response to fenofibrate (LDL cholesterol levels) ( 27002377)
  • Waist circumference ( 28552196)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for body mass index ( 28552196 28448500)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes 59 interacting genes: ACVRL1 AGR3 ANGPTL4 APP BCAS3 BGN BLID BMP2 BMP3 CCDC33 CCL3 CCL5 CCN2 COL2A1 CST6 DAXX DCN DIRAS3 DPT EIF3I ENG FCN1 FKBP1A FMOD FNTA GREB1 HOXC6 ITGAV ITGB6 ITGB8 KLK5 KLK7 KLK9 LAMTOR5 LTBP1 LTBP3 LTBP4 MEOX2 MMP2 MTA3 NSD3 PDLIM2 PRSS50 PSMC3IP PZP SCGB3A1 SDC2 SNAI1 SPARC ST14 TGFB2 TGFBR1 TGFBR2 TGFBR3 THBS1 THRSP VASN VTN YWHAE 10 interacting genes: APC APP BCAR3 BRD2 CHEK2 FGFR2 HMGB1 IGF1R PTPRJ TGFB1
Entrez ID 7040 3223
HPRD ID 01821 00858
Ensembl ID ENSG00000105329 ENSG00000197757
Uniprot IDs A0A499FJK2 P01137 P09630
PDB IDs 1KLA 1KLC 1KLD 3KFD 4KV5 5FFO 5VQP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?