TGFB1 and THBS1

  • Number of citations of the paper that reports this interaction (PubMedID 1550960)
  • 61

TGFB1

THBS1

Description transforming growth factor beta 1 thrombospondin 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Colorectal cancer ( 27145994 24836286)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Coronary artery disease ( 29212778 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Hematuria ( 30476138)
  • Hematuria (mild) ( 30476138)
  • Hematuria (moderate to severe) ( 30476138)
  • Preterm birth (maternal effect) ( 28877031)
  • Pulse pressure ( 30578418)
  • Type 2 diabetes ( 31049640)
  • Logical memory (immediate recall) in normal cognition ( 29274321)
  • Urate levels ( 31578528)
Interacting Genes 59 interacting genes: ACVRL1 AGR3 ANGPTL4 APP BCAS3 BGN BLID BMP2 BMP3 CCDC33 CCL3 CCL5 CCN2 COL2A1 CST6 DAXX DCN DIRAS3 DPT EIF3I ENG FCN1 FKBP1A FMOD FNTA GREB1 HOXC6 ITGAV ITGB6 ITGB8 KLK5 KLK7 KLK9 LAMTOR5 LTBP1 LTBP3 LTBP4 MEOX2 MMP2 MTA3 NSD3 PDLIM2 PRSS50 PSMC3IP PZP SCGB3A1 SDC2 SNAI1 SPARC ST14 TGFB2 TGFBR1 TGFBR2 TGFBR3 THBS1 THRSP VASN VTN YWHAE 40 interacting genes: CALCR CALR CD36 CD47 CFH COL1A1 COL2A1 COL3A1 COL4A1 COL5A1 COL7A1 CORO1A CTSG DCN DHFR ELANE F2 FGA FGF2 FN1 HRG IGFBP5 ITGB3 JAG1 KNG1 LAMB3 LRP1 LRP2 LRP5 MMP2 MMP9 MTDH PDGFB PLG SCARB2 SPARC TFPI TGFB1 TNFAIP6 TNFRSF11B
Entrez ID 7040 7057
HPRD ID 01821 01765
Ensembl ID ENSG00000105329 ENSG00000137801
Uniprot IDs A0A499FJK2 P01137 P07996
PDB IDs 1KLA 1KLC 1KLD 3KFD 4KV5 5FFO 5VQP 1LSL 1UX6 1Z78 1ZA4 2ERF 2ES3 2OUH 2OUJ 3R6B 5FOE
Enriched GO Terms of Interacting Partners?
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