TEAD4 and RABGEF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TEAD4	RABGEF1
Description		TEA domain transcription factor 4	RAB guanine nucleotide exchange factor 1
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex	Nucleolus Early Endosome Cytosol Early Endosome Membrane Recycling Endosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	DNA Binding Protein Binding Zinc Ion Binding Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding
	Biological Process	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Muscle Organ Development Hippo Signaling Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development	Protein Targeting To Membrane Endocytosis
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription	TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Narcolepsy with cataplexy ( 23496005)	Aortic root size ( 21223598) Central corneal thickness ( 29760442)
Interacting Genes		29 interacting genes: CCDC172 CCDC85B CCNDBP1 CEP55 CEP70 CTBP1 EXOC3-AS1 FBXO7 GOLGA2 HOMEZ KIAA0753 KRT40 KRTAP10-3 LZTS2 MDFI MTUS2 MYH7 PDE4DIP PFKM PNMA1 RABGEF1 RUNDC3A SSX2IP TRAF1 TRIM27 VGLL1 VPS52 WWTR1 YAP1	29 interacting genes: AP1G1 BLOC1S6 CIPC DAZAP2 DGCR6 DNAJC5 GGA1 GGA2 HRAS KXD1 MON1A MON1B RAB33B RAB4A RABEP1 RNF11 RNF168 RPS27A TEAD4 THOC1 TRIM15 TRIM54 TXN2 UBB UBC UBE2D1 UBE2D3 YWHAB ZC2HC1C
Entrez ID		7004	27342
HPRD ID		03421	11477
Ensembl ID		ENSG00000197905	ENSG00000154710
Uniprot IDs		Q15561	A0A024RDL6 A0A0A0MSJ3 A8K3R3 B3KMF1 Q9UJ41
PDB IDs		5GZB 5NO6 5OAQ 6GE3 6GE4 6GE5 6GE6 6GEC 6GEE 6GEG 6GEI 6GEK 6HIK 6Q2X 6Q36 6SEN 6SEO	1TXU 2C7M 2C7N 2OT3 4N3X 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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