STK3 and RASSF1

Number of citations of the paper that reports this interaction (PubMedID 28205554)
32

Data Source:
BioGRID (fluorescent resonance energy transfer)

		STK3	RASSF1
Description		serine/threonine kinase 3	Ras association domain family member 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Protein-containing Complex	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Microtubule Cytoskeleton
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity	Protein Binding Zinc Ion Binding
	Biological Process	Neural Tube Formation Endocardium Development Protein Phosphorylation Apoptotic Process Signal Transduction Regulation Of Mitotic Cell Cycle Central Nervous System Development Negative Regulation Of Cell Proliferation Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Protein Binding Activation Of Protein Kinase Activity Hippo Signaling Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of Organ Growth Neuron Projection Morphogenesis Protein Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Protein Kinase B Signaling Primitive Hemopoiesis Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Canonical Wnt Signaling Pathway Hepatocyte Apoptotic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Cell Cycle Arrest Ras Protein Signal Transduction Regulation Of Microtubule Cytoskeleton Organization
Pathways		Signaling by Hippo
Drugs
Diseases			Non-small cell lung cancer Bladder cancer Nasopharyngeal cancer
GWAS		Depressive symptom improvement ( 30468137) Heel bone mineral density ( 30598549) Rosacea symptom severity ( 29771307) Suicide behavior ( 26079190)	Schizophrenia ( 28991256 30285260) Sleep duration (short sleep) ( 30846698)
Interacting Genes		34 interacting genes: AKT1 CASP3 CDK1 CNKSR1 CPNE1 DDAH2 EIF4EBP1 FAM9B GAD1 GBP2 GMCL1 HSPE1 KEAP1 KHSRP LATS1 LATS2 LRRK2 MBP MOB4 MPP1 ORM2 PEX19 PHAX PLK1 QARS1 RAF1 RASSF1 SAV1 SLMAP STK4 SULT2A1 TFPT TRAF1 ZC3H7A	70 interacting genes: AKT1 ARAF ATM ATP2B4 ATR ATRX AURKA AURKB BRAF C7orf25 C8orf33 CCND2 CCNE1 CDC20 CDK4 CDK6 CDKN2A CDKN2B CLNK CNKSR1 DAXX DDB1 E4F1 EPHA2 ERBB2 EXOSC8 FGFR4 FZR1 GLIS2 GRM1 HRAS IGFBP5 KAT2A KCNE3 KDELR2 KDM1A LATS2 MAP1B MAP1S MAP2K3 MAP2K6 MAPK8 MDM2 MET MOAP1 MST1 MYC NF2 NUDT10 PRKDC RAF1 RASSF5 RELA RHOA RHOU SAV1 SMARCA4 STK11 STK3 STK4 SUV39H1 SUV39H2 TEAD2 TERT TNFRSF10A TNFRSF1A TSC1 TUBB TUBG1 XPA
Entrez ID		6788	11186
HPRD ID		05433	05470
Ensembl ID		ENSG00000104375	ENSG00000068028
Uniprot IDs		A0A087WZ06 A0A384MR07 Q13188	Q9NS23
PDB IDs		3WWS 4HKD 4L0N 4LG4 4LGD 4OH9 5BRM 5DH3 6AO5 6AR2	2KZU
Enriched GO Terms of Interacting Partners?
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