RASSF1 and SAV1

Number of citations of the paper that reports this interaction (PubMedID 17379520)
83

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		RASSF1	SAV1
Description		Ras association domain family member 1	salvador family WW domain containing protein 1
Image
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Microtubule Cytoskeleton	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding Identical Protein Binding Molecular Adaptor Activity
	Biological Process	Cell Cycle Arrest Ras Protein Signal Transduction Regulation Of Microtubule Cytoskeleton Organization	Hair Follicle Development Apoptotic Process Signal Transduction Keratinocyte Differentiation Hippo Signaling Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Negative Regulation Of Epithelial Cell Proliferation Protein Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Cardiac Muscle Cell Proliferation Ventricular Septum Morphogenesis Lung Epithelial Cell Differentiation Intestinal Epithelial Cell Differentiation Regulation Of Stem Cell Population Maintenance
Pathways			Signaling by Hippo
Drugs
Diseases		Non-small cell lung cancer Bladder cancer Nasopharyngeal cancer
GWAS		Schizophrenia ( 28991256 30285260) Sleep duration (short sleep) ( 30846698)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Dupuytren's disease ( 28886342) Heel bone mineral density ( 30598549) Lupus nephritis in systemic lupus erythematosus ( 24925725) Mean platelet volume ( 27863252) Periodontal disease-related phenotype (Socransky) ( 24347629) Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457)
Interacting Genes		70 interacting genes: AKT1 ARAF ATM ATP2B4 ATR ATRX AURKA AURKB BRAF C7orf25 C8orf33 CCND2 CCNE1 CDC20 CDK4 CDK6 CDKN2A CDKN2B CLNK CNKSR1 DAXX DDB1 E4F1 EPHA2 ERBB2 EXOSC8 FGFR4 FZR1 GLIS2 GRM1 HRAS IGFBP5 KAT2A KCNE3 KDELR2 KDM1A LATS2 MAP1B MAP1S MAP2K3 MAP2K6 MAPK8 MDM2 MET MOAP1 MST1 MYC NF2 NUDT10 PRKDC RAF1 RASSF5 RELA RHOA RHOU SAV1 SMARCA4 STK11 STK3 STK4 SUV39H1 SUV39H2 TEAD2 TERT TNFRSF10A TNFRSF1A TSC1 TUBB TUBG1 XPA	5 interacting genes: EP300 NEDD4 RASSF1 STK3 STK4
Entrez ID		11186	60485
HPRD ID		05470	06229
Ensembl ID		ENSG00000068028	ENSG00000151748
Uniprot IDs		Q9NS23	B3KTQ1 Q9H4B6
PDB IDs		2KZU	6AO5
Enriched GO Terms of Interacting Partners?
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