BNIP3 and BCL2L2

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		BNIP3	BCL2L2
Description		BCL2 interacting protein 3	BCL2 like 2
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Postsynaptic Density Dendrite Integral Component Of Mitochondrial Outer Membrane Mitochondrial Membrane	Mitochondrial Outer Membrane Cytosol Bcl-2 Family Protein Complex
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity GTPase Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity BH Domain Binding Disordered Domain Specific Binding
	Biological Process	Autophagy Of Mitochondrion Response To Hypoxia Apoptotic Process Cell Death Granzyme-mediated Apoptotic Signaling Pathway Response To Bacterium Positive Regulation Of Autophagy Negative Regulation Of Mitochondrial Fusion Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Necrotic Cell Death Viral Process Positive Regulation Of Macroautophagy Cerebral Cortex Development Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Complex Disassembly Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Membrane Potential Regulation Of Mitochondrial Membrane Permeability Autophagic Cell Death Response To Axon Injury Oligodendrocyte Differentiation Brown Fat Cell Differentiation Neuron Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Defense Response To Virus Response To Hyperoxia Negative Regulation Of Cell Death Cellular Response To Hydrogen Peroxide Cellular Response To Mechanical Stimulus Cellular Response To Cobalt Ion Cellular Response To Hypoxia Reactive Oxygen Species Metabolic Process Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Response To Oxygen-glucose Deprivation Mitochondrial Outer Membrane Permeabilization Toxin Transport Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Autophagy Of Mitochondrion Regulation Of Aerobic Respiration Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Reactive Oxygen Species Metabolic Process	Response To Ischemia Spermatogenesis Brain Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Apoptotic Process Sertoli Cell Proliferation Cellular Response To Estradiol Stimulus Negative Regulation Of Release Of Cytochrome C From Mitochondria Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cellular Response To Amyloid-beta Cellular Response To Glycine Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs			Navitoclax
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Metabolite levels ( 23823483)	Height ( 28552196)
Interacting Genes		21 interacting genes: BCL2 BCL2L1 BCL2L2 BNIP3L CD47 CLEC7A CLN8 CREB3 FATE1 HIF1A HIVEP1 KTN1 LDLRAD1 LMNA MAP1LC3B NCBP1 OPA1 RHEB TGM2 TMEM11 TUBGCP2	17 interacting genes: BAD BAX BBC3 BCL2L11 BID BIK BMF BNIP3 FATE1 HRK KASH5 LMNA PPP1CA S100B TCF4 TEX11 TP53
Entrez ID		664	599
HPRD ID		04482	03569
Ensembl ID		ENSG00000176171	ENSG00000129473
Uniprot IDs		Q12983 Q6NVY4	Q92843
PDB IDs		2J5D 2KA1 2KA2	1MK3 1O0L 1ZY3 2Y6W 4CIM
Enriched GO Terms of Interacting Partners?
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