SNRPB2 and SMN2

Number of citations of the paper that reports this interaction (PubMedID 9323129)
187

Data Source:
HPRD (in vitro)

		SNRPB2	SMN2
Description		small nuclear ribonucleoprotein polypeptide B2	survival of motor neuron 2, centromeric
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP U2 SnRNP Nuclear Speck Cytoplasmic Ribonucleoprotein Granule U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Nuclear Body Z Disc Axon SMN Complex SMN-Sm Protein Complex Cytoplasmic Ribonucleoprotein Granule Neuron Projection Perikaryon Gemini Of Coiled Bodies
	Molecular Function	Protein Binding U1 SnRNA Binding SnRNP Binding	RNA Binding Protein Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly DNA-templated Transcription, Termination Nervous System Development Import Into Nucleus
Pathways		mRNA Splicing - Major Pathway	snRNP Assembly
Drugs			Nusinersen
Diseases			Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
GWAS		Food allergy (maternal genetic effects) ( 29489655) Metabolite levels ( 23823483) Response to haloperidol in schizophrenia ( 29503163)
Interacting Genes		17 interacting genes: CALM1 CSDE1 DHX9 GABPB1 GOLGA2 HMBOX1 HNRNPUL1 HOMEZ HTATSF1 MCM6 MTUS2 PNMA1 SMN2 SNRPA1 SUGP1 TRIM27 ZBTB14	25 interacting genes: BLOC1S6 BYSL CHTOP DDX20 DHX9 FAM9B FBL GAR1 GEMIN2 HNRNPUL1 POLR1C POLR2A PPIG SMN1 SNRPB SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG TIAL1 USP9X VPS28
Entrez ID		6629	6607
HPRD ID		04628	09036
Ensembl ID		ENSG00000125870	ENSG00000205571
Uniprot IDs		P08579	B4DP61 E7EQZ4 Q16637
PDB IDs		1A9N 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QX9	1G5V 1MHN 2LEH 4A4E 4A4G 4GLI 4QQ6 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU
Enriched GO Terms of Interacting Partners?
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