SNRPA and U2AF2

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		SNRPA	U2AF2
Description		small nuclear ribonucleoprotein polypeptide A	U2 small nuclear RNA auxiliary factor 2
Image
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U1 SnRNP	Commitment Complex Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck U2-type Prespliceosome U2AF
	Molecular Function	RNA Binding Protein Binding U1 SnRNA Binding Identical Protein Binding U1 SnRNP Binding	RNA Binding Protein Binding Poly-pyrimidine Tract Binding Enzyme Binding Pre-mRNA 3'-splice Site Binding C2H2 Zinc Finger Domain Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of MRNA Polyadenylation	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing Negative Regulation Of Protein Ubiquitination Positive Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Malonic acid
Diseases
GWAS		Blood protein levels ( 28240269) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Hematocrit ( 27863252) melanoma-derived growth regulatory protein levels ( 25147954) Post bronchodilator FEV1 ( 26634245)	Menopause (age at onset) ( 26414677)
Interacting Genes		28 interacting genes: CDKN2A CIRBP DAPK1 EEF1AKNMT ENOX2 FBXO7 GABPB1 HNRNPK IL7R LENG8 MTUS2 NDUFAF3 PAPOLA PCBP1 PCBP2 PTBP1 PTBP2 QKI RBM3 RBM42 RBMX SFPQ SMAD5 TRIM27 TRIR U2AF2 UBC WBP4	47 interacting genes: APBB1 ATXN1 BEND7 CCAR1 CHERP CHIC2 CPSF7 DACH1 DDX6 DPPA2 DVL2 EPB41 GEMIN2 GLIS2 HLA-DMA IL7R KHDC4 KHDRBS3 LURAP1 MAP1B OTUB2 PIN1 POLR2A PRPF3 PRPF40A PUF60 QKI RBFOX2 RBM39 RBM4 SAP30BP SCAF11 SF1 SMAD5 SNRPA SRPK1 SRPK2 SRSF1 SRSF11 SUGP1 TCERG1 THAP1 TLE5 TOP1 U2AF1 WT1 ZRSR2
Entrez ID		6626	11338
HPRD ID		01658	01872
Ensembl ID		ENSG00000077312	ENSG00000063244
Uniprot IDs		P09012	P26368
PDB IDs		1AUD 1DRZ 1DZ5 1FHT 1M5K 1M5O 1M5P 1M5V 1NU4 1OIA 1SJ3 1SJ4 1SJF 1U6B 1URN 1VBX 1VBY 1VBZ 1VC0 1VC5 1VC6 1ZZN 2A3J 2NZ4 2OIH 2OJ3 2U1A 3BO2 3BO3 3BO4 3CUL 3CUN 3EGZ 3G8S 3G8T 3G96 3G9C 3HHN 3IIN 3IRW 3IWN 3K0J 3L3C 3MUM 3MUR 3MUT 3MUV 3MXH 3P49 3PGW 3R1H 3R1L 3UCU 3UCZ 3UD3 3UD4 3UTR 4C4W 4PR6 4PRF 4W90 4W92 4YB1 5DDO 5DDP 5DDQ 5DDR 5FJ4 6QX9	1JMT 1O0P 1OPI 1U2F 2G4B 2HZC 2M0G 2U2F 2YH0 2YH1 3VAF 3VAG 3VAH 3VAI 3VAJ 3VAK 3VAL 3VAM 4FXW 4TU7 4TU8 4TU9 5EV1 5EV2 5EV3 5EV4 5W0G 5W0H
Enriched GO Terms of Interacting Partners?
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