SNRPA and QKI

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SNRPA	QKI
Description		small nuclear ribonucleoprotein polypeptide A	QKI, KH domain containing RNA binding
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U1 SnRNP	Nucleus Cytoplasm Synapse
	Molecular Function	RNA Binding Protein Binding U1 SnRNA Binding Identical Protein Binding U1 SnRNP Binding	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of MRNA Polyadenylation	Vasculogenesis MRNA Processing Regulation Of Translation Spermatid Development RNA Splicing Positive Regulation Of Gene Expression Myelination Muscle Cell Differentiation Long-chain Fatty Acid Biosynthetic Process MRNA Transport
Pathways		mRNA Splicing - Major Pathway	Signaling by BRAF and RAF fusions
Drugs		Malonic acid
Diseases
GWAS		Blood protein levels ( 28240269) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Hematocrit ( 27863252) melanoma-derived growth regulatory protein levels ( 25147954) Post bronchodilator FEV1 ( 26634245)	Diastolic blood pressure ( 27841878) Diisocyanate-induced asthma ( 25918132) Height ( 31562340) Incident myocardial infarction ( 26950853) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Red blood cell count ( 29403010) Response to TNF antagonist treatment ( 18615156) Seasonality and depression ( 30217971) Type 2 diabetes ( 30297969 30718926)
Interacting Genes		28 interacting genes: CDKN2A CIRBP DAPK1 EEF1AKNMT ENOX2 FBXO7 GABPB1 HNRNPK IL7R LENG8 MTUS2 NDUFAF3 PAPOLA PCBP1 PCBP2 PTBP1 PTBP2 QKI RBM3 RBM42 RBMX SFPQ SMAD5 TRIM27 TRIR U2AF2 UBC WBP4	42 interacting genes: APP ATXN1 CARM1 CCND3 CDKN2D DAZ1 DAZ4 DEPP1 DMRTB1 FBXO7 FHL3 FUBP3 HCLS1 HNRNPH2 HNRNPK IL7R LSM3 NABP1 PCBP1 PCBP2 PCBP4 PIAS1 PRMT1 PSMF1 PTBP1 PTBP2 RALY RBFOX1 RBFOX2 RBM11 RBM14 RBM23 RBPMS RNF138 SERF2 SNRPA TEX11 THAP1 TSG101 U2AF2 USH1C WDR77
Entrez ID		6626	9444
HPRD ID		01658	06691
Ensembl ID		ENSG00000077312	ENSG00000112531
Uniprot IDs		P09012	Q8WY44 Q96PU8
PDB IDs		1AUD 1DRZ 1DZ5 1FHT 1M5K 1M5O 1M5P 1M5V 1NU4 1OIA 1SJ3 1SJ4 1SJF 1U6B 1URN 1VBX 1VBY 1VBZ 1VC0 1VC5 1VC6 1ZZN 2A3J 2NZ4 2OIH 2OJ3 2U1A 3BO2 3BO3 3BO4 3CUL 3CUN 3EGZ 3G8S 3G8T 3G96 3G9C 3HHN 3IIN 3IRW 3IWN 3K0J 3L3C 3MUM 3MUR 3MUT 3MUV 3MXH 3P49 3PGW 3R1H 3R1L 3UCU 3UCZ 3UD3 3UD4 3UTR 4C4W 4PR6 4PRF 4W90 4W92 4YB1 5DDO 5DDP 5DDQ 5DDR 5FJ4 6QX9	4JVH
Enriched GO Terms of Interacting Partners?
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