MTMR9 and SPG21

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		MTMR9	SPG21
Description		myotubularin related protein 9	SPG21 abhydrolase domain containing, maspardin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Ruffle Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm	Golgi Apparatus Cytosol Endosome Membrane Trans-Golgi Network Transport Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein Phosphatase Binding Enzyme Regulator Activity	Protein Binding CD4 Receptor Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Endocytosis Negative Regulation Of Autophagy Positive Regulation Of Phosphatase Activity Protein Stabilization Regulation Of Phosphatidylinositol Dephosphorylation	Antigen Receptor-mediated Signaling Pathway
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the late endosome membrane Synthesis of IP2, IP, and Ins in the cytosol
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS		Adventurousness ( 30643258) Bone ultrasound measurement (broadband ultrasound attenuation) ( 28472463) Extraversion ( 27918536) General factor of neuroticism ( 30867560) Retinal vascular caliber ( 21060863) Systemic lupus erythematosus ( 26316170)
Interacting Genes		16 interacting genes: AATK EMILIN1 ERBB3 ERBB4 EWSR1 KDM1A LNX1 MOS MTMR6 MTMR7 MTMR8 NMI PTK7 ROR2 SPG21 VAC14	37 interacting genes: AGTRAP AKIRIN2 ARL6IP1 CCDC102B CCDC33 CD4 CMTM5 CRYAA CTPS2 CUTC DTX2 DTX3L EFHC2 FAM114A1 GGA2 GSK3A IKZF3 INCA1 KRT15 LMNA MID2 MTMR9 PRPS1 RABAC1 REEP6 RTN4 S100B SPRED2 TCF12 TCF4 TFG TRAF1 TRAF2 TRIM23 TRIM54 TRIM9 ZNF263
Entrez ID		66036	51324
HPRD ID		09377	10492
Ensembl ID		ENSG00000104643	ENSG00000090487
Uniprot IDs		Q96QG7	A0A024R5Y1 Q9NZD8
PDB IDs
Enriched GO Terms of Interacting Partners?
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