UBE2Z and RNF130

Number of citations of the paper that reports this interaction (PubMedID 19690564)
57

Data Source:
BioGRID (two hybrid)

		UBE2Z	RNF130
Description		ubiquitin conjugating enzyme E2 Z	ring finger protein 130
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Cytoplasm Integral Component Of Membrane
	Molecular Function	Cysteine-type Endopeptidase Inhibitor Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Ubiquitin-protein Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Negative Regulation Of Endopeptidase Activity Protein Ubiquitination Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process	Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Programmed Cell Death Protein Ubiquitination
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 21378990) Height ( 31562340) Myocardial infarction ( 26343387) Type 2 diabetes ( 30054458 29358691)	LDL cholesterol ( 21347282) Pre-treatment viral load in HIV-1 infection ( 31219150) Systolic blood pressure ( 30224653)
Interacting Genes		34 interacting genes: AK8 BMPR1B DZIP3 HLTF HMBOX1 LNX2 LPL MDM2 OTUB1 PLEKHF2 PPP1CA PRKN RAPSN REL RNF103 RNF130 RNF139 RNF144B RNF150 RNF166 RNF41 RNF5 SMAD1 SMAD4 SRA1 SYVN1 TGFBR1 TRAIP TRIM27 TRIM46 TRIM65 UBA1 UBA6 UBD	13 interacting genes: ARPC4 FGFR3 SCN2A TGFBR1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2Z
Entrez ID		65264	55819
HPRD ID		08589	11504
Ensembl ID		ENSG00000159202	ENSG00000113269
Uniprot IDs		Q9H832	E5RI87 Q2HIY3 Q86XS8
PDB IDs		5A4P
Enriched GO Terms of Interacting Partners?
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