SLA and PAFAH1B2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		SLA	PAFAH1B2
Description		Src like adaptor	platelet activating factor acetylhydrolase 1b catalytic subunit 2
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GO Annotations	Cellular Component	Endosome Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Non-membrane Spanning Protein Tyrosine Kinase Activity SH3/SH2 Adaptor Activity Signaling Receptor Binding Protein Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding Platelet-activating Factor Acetyltransferase Activity
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Cell Differentiation Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation	Lipid Metabolic Process Spermatogenesis Brain Development Lipid Catabolic Process Positive Regulation Of Macroautophagy Neutrophil Degranulation
Pathways			Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Bone erosion in rheumatoid arthritis ( 28512992) Graves' disease ( 23612905) Multiple sclerosis ( 31604244) Temperament ( 22832960) Vitiligo ( 27723757 22561518)	Blood protein levels ( 28240269 23696881) HDL cholesterol ( 24507774) Protein quantitative trait loci ( 18464913) Systolic blood pressure ( 30578418)
Interacting Genes		14 interacting genes: CBL CD247 EGFR EPHA2 ERBB2 FGFR1 FLT3 GSK3B LAT PAFAH1B2 SYK UBE4A VAV1 ZAP70	16 interacting genes: ACIN1 ASF1A CCT3 CRK PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 ZFP36L1
Entrez ID		6503	5049
HPRD ID		03060	03940
Ensembl ID		ENSG00000155926	ENSG00000168092
Uniprot IDs		Q13239	P68402 V9HW44
PDB IDs		2CUD	1VYH
Enriched GO Terms of Interacting Partners?
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