TBC1D15 and RAB5B

Number of citations of the paper that reports this interaction (PubMedID 16923123)
61

Data Source:
BioGRID (two hybrid)

		TBC1D15	RAB5B
Description		TBC1 domain family member 15	RAB5B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm	Intracellular Endosome Early Endosome Plasma Membrane Endomembrane System Membrane Endocytic Vesicle Secretory Granule Membrane Early Endosome Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Rab GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding
	Biological Process	Intracellular Protein Transport Regulation Of GTPase Activity Activation Of GTPase Activity Regulation Of Cilium Assembly	Intracellular Protein Transport Endocytosis Endosome Organization Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Neutrophil Degranulation Plasma Membrane To Endosome Transport
Pathways		TBC/RABGAPs	Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Inferior parietal cortex volume ( 31530798) Metabolite levels ( 23823483)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 30929738 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive function ( 25644384) FEV1 ( 30804560) Gastroesophageal reflux disease ( 31527586) Lung function (FEV1) ( 30061609) Lung function (FEV1/FVC) ( 30804560) Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease) ( 31015401) Polycystic ovary syndrome ( 22885925 30566500) Sum eosinophil basophil counts ( 27863252) Type 1 diabetes ( 18198356) Vitiligo ( 22951725)
Interacting Genes		8 interacting genes: CALCOCO1 CEP63 FIS1 OPTN RAB5A RAB5B RAB5C UBC	17 interacting genes: APOA5 CDK1 CHM EEA1 GLP1R PIK3CB PRIM1 RABAC1 REEP5 RIN1 RIN2 RIN3 SGSM3 SUN2 TBC1D15 TBC1D17 TFRC
Entrez ID		64786	5869
HPRD ID		15470	01544
Ensembl ID		ENSG00000121749	ENSG00000111540
Uniprot IDs		A8K8E1 Q8TC07	A0A024RB09 P61020
PDB IDs			2HEI
Enriched GO Terms of Interacting Partners?
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