RAB5B and RIN2

Number of citations of the paper that reports this interaction (PubMedID 11733506)
32

Data Source:
HPRD (in vitro, two hybrid)

		RAB5B	RIN2
Description		RAB5B, member RAS oncogene family	Ras and Rab interactor 2
Image			No pdb structure
GO Annotations	Cellular Component	Intracellular Endosome Early Endosome Plasma Membrane Endomembrane System Membrane Endocytic Vesicle Secretory Granule Membrane Early Endosome Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane	Cellular_component Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding	GTPase Activator Activity Rab Guanyl-nucleotide Exchange Factor Activity GTPase Regulator Activity
	Biological Process	Intracellular Protein Transport Endocytosis Endosome Organization Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Neutrophil Degranulation Plasma Membrane To Endosome Transport	Endocytosis Small GTPase Mediated Signal Transduction Positive Regulation Of Endothelial Cell Migration Positive Regulation Of GTPase Activity Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Positive Regulation Of Vasculogenesis
Pathways		Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Macrocephaly, alopecia, cutis laxa, and scoliosis; MACS syndrome
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 30929738 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive function ( 25644384) FEV1 ( 30804560) Gastroesophageal reflux disease ( 31527586) Lung function (FEV1) ( 30061609) Lung function (FEV1/FVC) ( 30804560) Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease) ( 31015401) Polycystic ovary syndrome ( 22885925 30566500) Sum eosinophil basophil counts ( 27863252) Type 1 diabetes ( 18198356) Vitiligo ( 22951725)	Bipolar disorder and schizophrenia ( 20889312) Bone mineral density (total hip) ( 29883787) HDL cholesterol ( 31170924) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Platelet distribution width ( 27863252) Smoking status (ever vs never smokers) ( 30643258) Verbal declarative memory ( 25648963) Weight ( 28552196)
Interacting Genes		17 interacting genes: APOA5 CDK1 CHM EEA1 GLP1R PIK3CB PRIM1 RABAC1 REEP5 RIN1 RIN2 RIN3 SGSM3 SUN2 TBC1D15 TBC1D17 TFRC	7 interacting genes: BIN1 CDKN2A EGFR ERBB2 RAB5A RAB5B RAB5C
Entrez ID		5869	54453
HPRD ID		01544	15249
Ensembl ID		ENSG00000111540	ENSG00000132669
Uniprot IDs		A0A024RB09 P61020	A1A4T0 Q8WYP3
PDB IDs		2HEI
Enriched GO Terms of Interacting Partners?
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