GIGYF1 and CNOT9

Number of citations of the paper that reports this interaction (PubMedID 20878056)
6

Data Source:
BioGRID (affinity chromatography technology, pull down)

		GIGYF1	CNOT9
Description		GRB10 interacting GYF protein 1	CCR4-NOT transcription complex subunit 9
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GO Annotations	Cellular Component	Protein-containing Complex	P-body Nucleus Cytosol Membrane CCR4-NOT Complex CCR4-NOT Core Complex Protein-containing Complex
	Molecular Function	Protein Binding	Epidermal Growth Factor Receptor Binding Protein Binding Kinase Binding Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Biological_process Insulin-like Growth Factor Receptor Signaling Pathway	Nuclear-transcribed MRNA Poly(A) Tail Shortening DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Sex Differentiation Negative Regulation Of Translation Cytokine-mediated Signaling Pathway Gene Silencing By RNA Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Nuclear Receptor Transcription Coactivator Activity
Pathways			Deadenylation of mRNA Activation of anterior HOX genes in hindbrain development during early embryogenesis TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Resting heart rate ( 27798624)
Interacting Genes		6 interacting genes: ATN1 CNOT9 EIF4E2 GRB10 GRB14 GRB7	8 interacting genes: AKT1 CNOT1 CNOT4 EGFR GIGYF1 GIGYF2 GRB10 MYB
Entrez ID		64599	9125
HPRD ID		10145	08828
Ensembl ID		ENSG00000146830	ENSG00000144580
Uniprot IDs		O75420	D5MQE1 Q92600
PDB IDs		5NVK	2FV2 4CRU 4CRV 4CT6 4CT7 5LSW 5ONA 5ONB 6HOM 6HON
Enriched GO Terms of Interacting Partners?
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