GIGYF1 and EIF4E2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology)

		GIGYF1	EIF4E2
Description		GRB10 interacting GYF protein 1	eukaryotic translation initiation factor 4E family member 2
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GO Annotations	Cellular Component	Protein-containing Complex	Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	Protein Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding
	Biological Process	Biological_process Insulin-like Growth Factor Receptor Signaling Pathway	In Utero Embryonic Development Translational Initiation Negative Regulation Of Translation
Pathways			ISG15 antiviral mechanism
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Resting heart rate ( 27798624)	Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520)
Interacting Genes		6 interacting genes: ATN1 CNOT9 EIF4E2 GRB10 GRB14 GRB7	51 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CAB39 CARD9 CBY2 CCL24 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MIPOL1 MVK MYOG NECAB2 NOTCH2NLA PDE4DIP PRDM14 REL SAG SP140 SPAG5 SPRY2 TADA2A TCF4 TGFBRAP1 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9
Entrez ID		64599	9470
HPRD ID		10145	05798
Ensembl ID		ENSG00000146830	ENSG00000135930
Uniprot IDs		O75420	B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1
PDB IDs		5NVK	2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN
Enriched GO Terms of Interacting Partners?
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