SCAF11 and SNRNP70

Number of citations of the paper that reports this interaction (PubMedID 9447963)
8

Data Source:
HPRD (two hybrid, in vitro)

		SCAF11	SNRNP70
Description		SR-related CTD associated factor 11	small nuclear ribonucleoprotein U1 subunit 70
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Nuclear Body	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding SnRNA Binding U1 SnRNA Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome Regulation Of ATPase Activity Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Refolding Negative Regulation Of Chaperone-mediated Autophagy
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Morning person ( 30696823) Multiple sclerosis ( 31604244) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Systolic blood pressure ( 30224653)
Interacting Genes		10 interacting genes: ATXN1L PSEN1 SNRNP70 SRPK1 SRSF1 SRSF2 SRSF3 SRSF4 STAT3 U2AF2	41 interacting genes: APP ARSF CDKL3 CEP63 CHERP CRP CTDP1 DDX17 GEMIN2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2
Entrez ID		9169	6625
HPRD ID		04720	01617
Ensembl ID		ENSG00000139218	ENSG00000104852
Uniprot IDs		Q99590	A0A024QZD5 P08621 Q9UFS1
PDB IDs			2L5I 2L5J 3CW1 3PGW 4PJO 4PKD 6QX9
Enriched GO Terms of Interacting Partners?
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