ENO1 and TRAPPC2

Number of citations of the paper that reports this interaction (PubMedID 11134351)
10

Data Source:
BioGRID (two hybrid, affinity chromatography technology, pull down)

		ENO1	TRAPPC2
Description		enolase 1	trafficking protein particle complex 2
Image			No pdb structure
GO Annotations	Cellular Component	Phosphopyruvate Hydratase Complex Extracellular Space Nucleus Cytoplasm Cytosol Plasma Membrane Cell Surface Membrane M Band Extracellular Exosome Cell Cortex Region	Golgi Membrane Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Magnesium Ion Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Binding Phosphopyruvate Hydratase Activity Protein Binding Protein Homodimerization Activity Cadherin Binding GTPase Binding	Protein Binding Transcription Factor Binding Ion Channel Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Gluconeogenesis Response To Virus Positive Regulation Of Plasminogen Activation Negative Regulation Of Cell Growth Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Muscle Contraction Canonical Glycolysis Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of ATP Biosynthetic Process	Skeletal System Development Regulation Of Transcription, DNA-templated ER To Golgi Vesicle-mediated Transport COPII Vesicle Coating
Pathways		Glycolysis Gluconeogenesis Manipulation of host energy metabolism	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		Zinc Copper Artenimol
Diseases			Spondyloepiphyseal dysplasia tarda
GWAS		Asthma ( 30929738) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blood protein levels ( 30072576) Feeling tense ( 29500382) Plateletcrit ( 27863252) Tonsillectomy ( 27182965 28928442) White blood cell count (basophil) ( 27863252)
Interacting Genes		26 interacting genes: AGTPBP1 AMBP BHLHE40 BRCA1 CHEK2 CLK1 FANCA FYN GRB2 HDAC1 HEMGN HSPB2 LIG4 MCPH1 MYOC PCNA PLG SERPING1 SRC SUMO2 SUMO4 TERT TRAPPC2 UPF2 YWHAQ YWHAZ	14 interacting genes: CLIC1 CLIC2 DAPK1 ENO1 MFHAS1 NR5A1 PITX1 TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9
Entrez ID		2023	6399
HPRD ID		01400	02189
Ensembl ID		ENSG00000074800	ENSG00000196459
Uniprot IDs		A0A024R4F1 P06733	P0DI81 P0DI82 Q6IBE5
PDB IDs		2PSN 3B97 5JLZ 5LAX 5NI9 5NIG 5OCK
Enriched GO Terms of Interacting Partners?
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