CLIP1 and TSC22D2

Number of citations of the paper that reports this interaction (PubMedID 27337956)
18

Data Source:
BioGRID (two hybrid)

		CLIP1	TSC22D2
Description		CAP-Gly domain containing linker protein 1	TSC22 domain family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Ruffle Nuclear Envelope Centrosome Cytosol Microtubule Cytoplasmic Microtubule Intermediate Filament Microtubule Cytoskeleton Cytoplasmic Vesicle Membrane Microtubule Plus-end Macropinosome
	Molecular Function	Protein Binding Microtubule Binding Zinc Ion Binding Tubulin Binding Microtubule Plus-end Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
	Biological Process	Mitotic Cell Cycle Microtubule Bundle Formation Positive Regulation Of Microtubule Polymerization Protein Transport Into Plasma Membrane Raft	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases activate IQGAPs RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body mass index ( 26961502 25673413) Chronotype ( 30696823) Hip circumference ( 25673412) Weight ( 28552196)	Adiponectin levels ( 22479202) Cognitive decline rate in late mild cognitive impairment ( 26252872) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 29891935) Intraocular pressure ( 29235454) Macular thickness ( 30535121) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Moyamoya disease ( 29273593) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Type 2 diabetes ( 30054458 30297969) Waist circumference ( 26785701)
Interacting Genes		11 interacting genes: BIN1 CALM1 CLASP2 DCTN1 IQGAP1 MAPRE2 MTOR PAFAH1B1 TSC22D2 TUBA1A TUBB	43 interacting genes: ANAPC10 ANKRD36 ARID2 ATP1B1 CCDC141 CCDC144A CLIP1 ENOPH1 EPCAM F8 FLNB GPBP1 ITGA2 KIAA0586 LOXHD1 LPL LRRC6 MED13 MPDZ MSH3 MTIF2 NGRN NRBP1 OSBPL1A PRMT3 PSMA7 PSMA8 RBL1 REV1 RNF2 SAP18 SCEL SEC31A SNX3 SPEF2 STK39 TMA7 TTN UFM1 WNK3 ZMYM2 ZNF143 ZNF251
Entrez ID		6249	9819
HPRD ID		01568	11101
Ensembl ID		ENSG00000130779	ENSG00000196428
Uniprot IDs		A0A024RBR1 B3KXA5 P30622	B4DN36 O75157
PDB IDs		2CP5 2CP6 2E3H 2E3I 2E4H 2HQH 2QK0 3E2U 3RDV
Enriched GO Terms of Interacting Partners?
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