CLIP1 and CLASP2

Number of citations of the paper that reports this interaction (PubMedID 11290329)
174

Data Source:
HPRD (two hybrid, in vitro)

		CLIP1	CLASP2
Description		CAP-Gly domain containing linker protein 1	cytoplasmic linker associated protein 2
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GO Annotations	Cellular Component	Kinetochore Ruffle Nuclear Envelope Centrosome Cytosol Microtubule Cytoplasmic Microtubule Intermediate Filament Microtubule Cytoskeleton Cytoplasmic Vesicle Membrane Microtubule Plus-end Macropinosome	Kinetochore Condensed Chromosome Kinetochore Cell Cytoplasm Golgi Apparatus Trans-Golgi Network Microtubule Organizing Center Kinetochore Microtubule Cytosol Microtubule Cytoplasmic Microtubule Plasma Membrane Focal Adhesion Cell Cortex Membrane Cell Leading Edge Ruffle Membrane Basal Cortex Mitotic Spindle
	Molecular Function	Protein Binding Microtubule Binding Zinc Ion Binding Tubulin Binding Microtubule Plus-end Binding	Dystroglycan Binding Protein Binding Microtubule Binding Microtubule Plus-end Binding
	Biological Process	Mitotic Cell Cycle Microtubule Bundle Formation Positive Regulation Of Microtubule Polymerization Protein Transport Into Plasma Membrane Raft	Microtubule Cytoskeleton Organization Vesicle Targeting Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Golgi Organization Mitotic Spindle Organization Establishment Or Maintenance Of Cell Polarity Exit From Mitosis Regulation Of Gastrulation Positive Regulation Of Epithelial Cell Migration Regulation Of Epithelial To Mesenchymal Transition Microtubule Organizing Center Organization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule-based Process Microtubule Anchoring Positive Regulation Of Exocytosis Cell Division Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation Of Basement Membrane Assembly Involved In Embryonic Body Morphogenesis
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases activate IQGAPs RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Role of ABL in ROBO-SLIT signaling RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body mass index ( 26961502 25673413) Chronotype ( 30696823) Hip circumference ( 25673412) Weight ( 28552196)	Metabolite levels ( 23823483)
Interacting Genes		11 interacting genes: BIN1 CALM1 CLASP2 DCTN1 IQGAP1 MAPRE2 MTOR PAFAH1B1 TSC22D2 TUBA1A TUBB	11 interacting genes: AKT1 CLIP1 CLIP2 CSNK2A1 FEZ1 FEZ2 MAPRE1 MAPRE2 MARK3 RBFOX2 SRPK2
Entrez ID		6249	23122
HPRD ID		01568	12054
Ensembl ID		ENSG00000130779	ENSG00000163539
Uniprot IDs		A0A024RBR1 B3KXA5 P30622	E3W994 E7ERI8 E7EW49 O75122
PDB IDs		2CP5 2CP6 2E3H 2E3I 2E4H 2HQH 2QK0 3E2U 3RDV	3WOY 5NR4
Enriched GO Terms of Interacting Partners?
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