PPCDC and TXN2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PPCDC	TXN2
Description		phosphopantothenoylcysteine decarboxylase	thioredoxin 2
Image
GO Annotations	Cellular Component	Cytosol	Cell Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body
	Molecular Function	Phosphopantothenoylcysteine Decarboxylase Activity Protein Binding Identical Protein Binding	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding
	Biological Process	Coenzyme Biosynthetic Process Coenzyme A Biosynthetic Process	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury Oxidation-reduction Process
Pathways		Coenzyme A biosynthesis	Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs		Riboflavin Monophosphate Pantothenoylaminoethenethiol
Diseases
GWAS		Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707) Heel bone mineral density ( 30598549) Systemic lupus erythematosus ( 26502338)
Interacting Genes		9 interacting genes: CENPT DBI FOXR1 NTAQ1 PPIG PSMA1 SREK1IP1 TXN2 ZNF232	35 interacting genes: AGTRAP ALDOB AP2B1 CCDC114 DCTD FAM9B GPRASP2 KRT18 KRT40 MAGEA11 MAPRE2 MAPRE3 MLH1 MRFAP1L1 MTUS2 PPCDC PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SCYL3 SHARPIN SSNA1 STUB1 SUN2 THAP1 TIFA TRIM21 TRIP6 UCHL5 VIM VPS52 ZBTB14
Entrez ID		60490	25828
HPRD ID		14377	07161
Ensembl ID		ENSG00000138621	ENSG00000100348
Uniprot IDs		H3BQB0 H3BRQ0 H3BSE3 H3BU63 Q96CD2	B4DX69 Q99757
PDB IDs		1QZU	1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?
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