TXN2 and TIFA

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TXN2	TIFA
Description		thioredoxin 2	TRAF interacting protein with forkhead associated domain
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GO Annotations	Cellular Component	Cell Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body	Cytoplasm
	Molecular Function	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding	Protein Binding
	Biological Process	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury Oxidation-reduction Process	Cytoplasmic Pattern Recognition Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Protein Homooligomerization
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species	Alpha-protein kinase 1 signaling pathway
Drugs
Diseases
GWAS			Body mass index ( 26426971) Rheumatoid arthritis ( 30891314)
Interacting Genes		35 interacting genes: AGTRAP ALDOB AP2B1 CCDC114 DCTD FAM9B GPRASP2 KRT18 KRT40 MAGEA11 MAPRE2 MAPRE3 MLH1 MRFAP1L1 MTUS2 PPCDC PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SCYL3 SHARPIN SSNA1 STUB1 SUN2 THAP1 TIFA TRIM21 TRIP6 UCHL5 VIM VPS52 ZBTB14	18 interacting genes: AP1M1 ARHGEF39 DVL2 IRAK1 LNX1 LNX2 NIF3L1 NUDT18 NXF1 RPL9 SDCBP SDCBP2 TIFAB TNFAIP8 TRAF1 TRAF2 TRAF6 TXN2
Entrez ID		25828	92610
HPRD ID		07161	09835
Ensembl ID		ENSG00000100348	ENSG00000145365
Uniprot IDs		B4DX69 Q99757	Q96CG3
PDB IDs		1UVZ 1W4V 1W89	4YM4 4ZGI 5ZUJ 6A33
Enriched GO Terms of Interacting Partners?
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