TXN2 and RPIA

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TXN2	RPIA
Description		thioredoxin 2	ribose 5-phosphate isomerase A
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body	Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding	Ribose-5-phosphate Isomerase Activity Protein Binding Identical Protein Binding Monosaccharide Binding
	Biological Process	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury Oxidation-reduction Process	D-ribose Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Non-oxidative Branch Ribose Phosphate Metabolic Process
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species	RPIA deficiency: failed conversion of R5P to RU5P RPIA deficiency: failed conversion of RU5P to R5P Pentose phosphate pathway
Drugs			4-phospho-L-threonic acid
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		35 interacting genes: AGTRAP ALDOB AP2B1 CCDC114 DCTD FAM9B GPRASP2 KRT18 KRT40 MAGEA11 MAPRE2 MAPRE3 MLH1 MRFAP1L1 MTUS2 PPCDC PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SCYL3 SHARPIN SSNA1 STUB1 SUN2 THAP1 TIFA TRIM21 TRIP6 UCHL5 VIM VPS52 ZBTB14	14 interacting genes: ATPAF2 CENPP FOXP2 FXR2 GORASP2 LNX1 NIF3L1 NTAQ1 PCMT1 PTPN11 RNF208 STK16 TXN2 VTA1
Entrez ID		25828	22934
HPRD ID		07161	01589
Ensembl ID		ENSG00000100348	ENSG00000153574
Uniprot IDs		B4DX69 Q99757	P49247
PDB IDs		1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?
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