RNF2 and AMBRA1

  • Number of citations of the paper that reports this interaction (PubMedID 24980959)
  • 27
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology, pull down, enzymatic study)

RNF2

AMBRA1

Description ring finger protein 2 autophagy and beclin 1 regulator 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Clopidogrel active metabolite levels ( 28207573)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Obesity-related traits ( 23251661)
  • Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 28552196)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Immunoglobulin A ( 20694011)
  • Normal facial asymmetry (angle of deformation score) ( 30631343)
  • Schizophrenia ( 28991256 29483656 30285260)
  • Selective IgA deficiency ( 27723758)
Interacting Genes 55 interacting genes: ABCB1 AMBRA1 AUTS2 BAALC BMI1 CASP3 CASP9 CBX2 CBX4 ERG H2AC18 H2AC20 H2AC4 H3-4 KAT8 KMT2A MBD1 MTNR1A OTUD6A PCGF2 PCGF6 PGP PHB2 PHC1 PHC2 PLK1 PSMC4 RING1 RRM1 RYBP SIK1 SMURF2 SSX2 TARDBP TFCP2 TSC22D2 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2J1 UBE2K UBE2L3 UBE2U UBE2V1 UBE2V2 UBE2W USP11 USP19 WASHC1 12 interacting genes: BECN1 CHUK GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C MTOR RNF2 SNCA UBE2D3
Entrez ID 6045 55626
HPRD ID 07028 10975
Ensembl ID ENSG00000121481 ENSG00000110497
Uniprot IDs Q99496 A0A075B6T1 Q9C0C7
PDB IDs 2H0D 3GS2 3H8H 3IXS 3RPG 4R8P 4S3O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?