RNASEL and TCF12

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RNASEL	TCF12
Description		ribonuclease L	transcription factor 12
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GO Annotations	Cellular Component	Cellular_component Mitochondrial Matrix Cytosol Nuclear Matrix	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle RNA Polymerase II Transcription Factor Complex
	Molecular Function	RNA Binding Endoribonuclease Activity Protein Kinase Activity Protein Binding ATP Binding RRNA Binding Ribonucleoprotein Complex Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Enhancer Binding CAMP Response Element Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Transcription Regulatory Region DNA Binding SMAD Binding Protein Heterodimerization Activity E-box Binding HMG Box Domain Binding
	Biological Process	RRNA Processing MRNA Processing Protein Phosphorylation Regulation Of MRNA Stability Negative Regulation Of Viral Genome Replication Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Glucose Import Defense Response To Virus Type I Interferon Signaling Pathway Regulation Of Type I Interferon-mediated Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Regulation Of Transcription By RNA Polymerase II Immune Response Muscle Organ Development Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		OAS antiviral response Interferon alpha/beta signaling	Myogenesis Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS		Morning vs. evening chronotype ( 26835600) Multiple sclerosis ( 23412934)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Alcohol consumption (drinks per week) ( 30643258) Body mass index ( 28892062) Glaucoma (primary open-angle) ( 29891935) Male-pattern baldness ( 28196072) Mean platelet volume ( 27863252) Type 2 diabetes ( 30297969)
Interacting Genes		3 interacting genes: ABCE1 AR TCF12	59 interacting genes: ACTB ADAM10 ARMC8 ASCL4 BCL2L10 BMERB1 BMF C1orf109 CDKN2C CFAP206 CRCP CREBBP DGCR6 EDRF1 EP300 FRMD6 HAND1 HOPX ID1 ID2 ID3 LYSMD1 MAPK6 MAPKBP1 MLLT6 MORN4 MSC MYF6 NAGK OLIG3 OSGIN1 PRSS23 PSMA1 PTF1A QARS1 RNASEL RSL24D1 RUNX1T1 SCG3 SLC12A1 SLC24A1 SOX10 SOX8 SPG21 SPTBN5 SRI STAT5A STK16 TAF4 TAL2 TBP TCF23 TCF3 TRIM72 TSNAX TWIST2 VPS28 YKT6 ZNF688
Entrez ID		6041	6938
HPRD ID		01590	02725
Ensembl ID		ENSG00000135828	ENSG00000140262
Uniprot IDs		Q05823	A0A024R5T1 A0A024R5Z0 F5GY10 Q99081
PDB IDs		1WDY 4G8K 4G8L 4OAU 4OAV	2KNH 4JOL
Enriched GO Terms of Interacting Partners?
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