SENP2 and TMEM239

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SENP2	TMEM239
Description		SUMO specific peptidase 2	transmembrane protein 239
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytosol PML Body Nuclear Membrane	Integral Component Of Membrane
	Molecular Function	Protein Binding SUMO-specific Protease Activity Protein Domain Specific Binding SUMO-specific Endopeptidase Activity SUMO-specific Isopeptidase Activity	Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Heart Development Dorsal/ventral Axis Specification Protein Transport Wnt Signaling Pathway Protein Sumoylation Protein Desumoylation Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Protein Destabilization Negative Regulation Of Protein Binding Regulation Of DNA Endoreduplication Negative Regulation Of Chromatin Binding Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II MRNA Transport Trophoblast Giant Cell Differentiation Labyrinthine Layer Development Spongiotrophoblast Layer Development Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		SUMO is proteolytically processed
Drugs
Diseases
GWAS		Diastolic blood pressure ( 28135244 27841878) Estimated glomerular filtration rate ( 31152163 31015462) Height ( 28552196) Hip circumference ( 28552196) PR interval ( 30046033) QRS duration ( 30012220) Seborrheic dermatitis ( 29203360) Systolic blood pressure ( 27841878 26969751)	Estimated glomerular filtration rate ( 31451708) Pulse pressure ( 30224653) White matter integrity ( 23218918)
Interacting Genes		28 interacting genes: AGTRAP APP ARL6IP1 AXIN1 CDCA5 CDK5RAP2 DAXX FUNDC1 FZR1 IKBKG KASH5 KPNA1 KPNB1 LMNA MYC NACC1 NEDD4L NUP153 PML RANGAP1 STK38 SUMO1 SUMO2 SUMO3 SYNE4 TMEM239 TPD52 TRIM63	12 interacting genes: ATF7 COQ8A CXCL16 FGD2 LENG1 MYG1 NTAQ1 POLI S100B SDCBP SENP2 USP5
Entrez ID		59343	100288797
HPRD ID		07002
Ensembl ID		ENSG00000163904	ENSG00000198326
Uniprot IDs		Q9HC62	Q8WW34
PDB IDs		1TGZ 1TH0 2IO0 2IO1 2IO2 2IO3 3ZO5 5AEK
Enriched GO Terms of Interacting Partners?
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