TMEM239 and FGD2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TMEM239	FGD2
Description		transmembrane protein 239	FYVE, RhoGEF and PH domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Ruffle Nucleus Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Lamellipodium Early Endosome Membrane Ruffle Membrane
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding
	Biological Process		Cytoskeleton Organization G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Apoptotic Process Regulation Of GTPase Activity Positive Regulation Of JUN Kinase Activity Filopodium Assembly Regulation Of Small GTPase Mediated Signal Transduction
Pathways			NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708) Pulse pressure ( 30224653) White matter integrity ( 23218918)	Acne (severe) ( 24927181) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Medication use (thyroid preparations) ( 31015401) Rosacea symptom severity ( 29771307)
Interacting Genes		12 interacting genes: ATF7 COQ8A CXCL16 FGD2 LENG1 MYG1 NTAQ1 POLI S100B SDCBP SENP2 USP5	2 interacting genes: KLHL12 TMEM239
Entrez ID		100288797	221472
HPRD ID			05478
Ensembl ID		ENSG00000198326	ENSG00000146192
Uniprot IDs		Q8WW34	Q7Z6J4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?