ACE2 and NTS

Number of citations of the paper that reports this interaction (PubMedID 11815627)
219

Data Source:
HPRD (in vitro)

		ACE2	NTS
Description		angiotensin I converting enzyme 2	neurotensin
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Brush Border Membrane Membrane Raft Extracellular Exosome	Extracellular Region Transport Vesicle Axon Terminus
	Molecular Function	Virus Receptor Activity Endopeptidase Activity Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Metallopeptidase Activity Exopeptidase Activity Dipeptidyl-peptidase Activity Peptidyl-dipeptidase Activity Zinc Ion Binding	Neuropeptide Hormone Activity Protein Binding
	Biological Process	Regulation Of Cytokine Production Angiotensin Maturation Angiotensin-mediated Drinking Behavior Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Tryptophan Transport Regulation Of Vasoconstriction Receptor Biosynthetic Process Regulation Of Cell Proliferation Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Regulation Of Inflammatory Response Positive Regulation Of Amino Acid Transport Positive Regulation Of Cardiac Muscle Contraction Regulation Of Blood Vessel Diameter Positive Regulation Of Gap Junction Assembly Regulation Of Cardiac Conduction Positive Regulation Of Reactive Oxygen Species Metabolic Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		Metabolism of Angiotensinogen to Angiotensins	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs		Moexipril SPP1148
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		4 interacting genes: AGT DLEU2 GHRL NTS	9 interacting genes: ACE2 ARRB2 CPE MEP1A NLN NTSR1 NTSR2 PREP SORT1
Entrez ID		59272	4922
HPRD ID		02274	08878
Ensembl ID		ENSG00000130234	ENSG00000133636
Uniprot IDs		Q9BYF1	P30990 Q6FH20
PDB IDs		1R42 1R4L 1XJP 2AJF 3D0G 3D0H 3D0I 3KBH 3SCI 3SCJ 3SCK 3SCL 6ACG 6ACJ 6ACK 6CS2	2LNE 2LNF 2LNG 2LYW 2OYV 2OYW 3F6K 4PO7 5LUZ
Enriched GO Terms of Interacting Partners?
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