NTS and ACE2

Number of citations of the paper that reports this interaction (PubMedID 11815627)
219

Data Source:
HPRD (in vitro)

		NTS	ACE2
Description		neurotensin	angiotensin I converting enzyme 2
Image
GO Annotations	Cellular Component	Extracellular Region Transport Vesicle Axon Terminus	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Brush Border Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Neuropeptide Hormone Activity Protein Binding	Virus Receptor Activity Endopeptidase Activity Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Metallopeptidase Activity Exopeptidase Activity Dipeptidyl-peptidase Activity Peptidyl-dipeptidase Activity Zinc Ion Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway	Regulation Of Cytokine Production Angiotensin Maturation Angiotensin-mediated Drinking Behavior Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Tryptophan Transport Regulation Of Vasoconstriction Receptor Biosynthetic Process Regulation Of Cell Proliferation Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Regulation Of Inflammatory Response Positive Regulation Of Amino Acid Transport Positive Regulation Of Cardiac Muscle Contraction Regulation Of Blood Vessel Diameter Positive Regulation Of Gap Junction Assembly Regulation Of Cardiac Conduction Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	Metabolism of Angiotensinogen to Angiotensins
Drugs			Moexipril SPP1148
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		9 interacting genes: ACE2 ARRB2 CPE MEP1A NLN NTSR1 NTSR2 PREP SORT1	4 interacting genes: AGT DLEU2 GHRL NTS
Entrez ID		4922	59272
HPRD ID		08878	02274
Ensembl ID		ENSG00000133636	ENSG00000130234
Uniprot IDs		P30990 Q6FH20	Q9BYF1
PDB IDs		2LNE 2LNF 2LNG 2LYW 2OYV 2OYW 3F6K 4PO7 5LUZ	1R42 1R4L 1XJP 2AJF 3D0G 3D0H 3D0I 3KBH 3SCI 3SCJ 3SCK 3SCL 6ACG 6ACJ 6ACK 6CS2
Enriched GO Terms of Interacting Partners?
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