ACE2 and DLEU2

Number of citations of the paper that reports this interaction (PubMedID 28977802)
3

Data Source:
BioGRID (affinity chromatography technology, unspecified method)

		ACE2	DLEU2
Description		angiotensin I converting enzyme 2	deleted in lymphocytic leukemia 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Brush Border Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Virus Receptor Activity Endopeptidase Activity Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Metallopeptidase Activity Exopeptidase Activity Dipeptidyl-peptidase Activity Peptidyl-dipeptidase Activity Zinc Ion Binding
	Biological Process	Regulation Of Cytokine Production Angiotensin Maturation Angiotensin-mediated Drinking Behavior Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Tryptophan Transport Regulation Of Vasoconstriction Receptor Biosynthetic Process Regulation Of Cell Proliferation Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Regulation Of Inflammatory Response Positive Regulation Of Amino Acid Transport Positive Regulation Of Cardiac Muscle Contraction Regulation Of Blood Vessel Diameter Positive Regulation Of Gap Junction Assembly Regulation Of Cardiac Conduction Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Metabolism of Angiotensinogen to Angiotensins
Drugs		Moexipril SPP1148
Diseases
GWAS			Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549) Height ( 28552196) Lipoprotein (a) levels ( 30108283) Third ventricle volume ( 31530798) Waist-to-hip ratio adjusted for body mass index ( 28430825)
Interacting Genes		4 interacting genes: AGT DLEU2 GHRL NTS	2 interacting genes: ACE2 CUL1
Entrez ID		59272	8847
HPRD ID		02274	16151
Ensembl ID		ENSG00000130234	ENSG00000231607
Uniprot IDs		Q9BYF1
PDB IDs		1R42 1R4L 1XJP 2AJF 3D0G 3D0H 3D0I 3KBH 3SCI 3SCJ 3SCK 3SCL 6ACG 6ACJ 6ACK 6CS2
Enriched GO Terms of Interacting Partners?
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