RAD51D and XRCC3

Number of citations of the paper that reports this interaction (PubMedID 11744692)
31

Data Source:
HPRD (in vitro, in vivo)

		RAD51D	XRCC3
Description		RAD51 paralog D	X-ray repair cross complementing 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Replication Fork Cytoplasm Centrosome Rad51B-Rad51C-Rad51D-XRCC2 Complex	Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Replication Fork Cytoplasm Mitochondrion Cytosol Rad51C-XRCC3 Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Four-way Junction DNA Binding DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Gamma-tubulin Binding	Four-way Junction DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Crossover Junction Endodeoxyribonuclease Activity
	Biological Process	Telomere Maintenance Double-strand Break Repair Via Homologous Recombination DNA Repair Reciprocal Meiotic Recombination Interstrand Cross-link Repair Strand Invasion Regulation Of Cell Cycle	Telomere Maintenance Via Recombination Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination Cellular Response To DNA Damage Stimulus Response To Organic Substance Regulation Of Centrosome Duplication Interstrand Cross-link Repair Double-strand Break Repair Via Synthesis-dependent Strand Annealing Resolution Of Mitotic Recombination Intermediates Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint T-circle Formation Telomeric Loop Disassembly Telomere Maintenance Via Telomere Trimming
Pathways		HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange TP53 Regulates Transcription of DNA Repair Genes	HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 26426971 29273807) Schizophrenia ( 25056061 29483656)
Interacting Genes		22 interacting genes: AMOTL2 BLM C1orf94 CCDC33 CEP57L1 EFHC2 IHO1 IKZF1 IKZF3 KIFC3 KRT15 LNX1 LZTS2 PRDM14 RAD51B RAD51C RHOU RNF138 SWSAP1 XRCC2 XRCC3 ZSWIM7	22 interacting genes: BAP1 BCAS3 CXCL1 FANCG GREB1 ITIH5 LRATD2 MRC2 OSGIN1 PALB2 PSMC3IP RAD51 RAD51C RAD51D RNF20 SCGB3A1 SERPINB5 SNAI1 SWSAP1 TFF1 ZNHIT3 ZSWIM7
Entrez ID		5892	7517
HPRD ID		04261	07201
Ensembl ID		ENSG00000185379	ENSG00000126215
Uniprot IDs		O75771	O43542 Q53XC8
PDB IDs		2KZ3
Enriched GO Terms of Interacting Partners?
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