RAD51D and RAD51B

Number of citations of the paper that reports this interaction (PubMedID 11751636)
83

Data Source:
HPRD (in vivo, in vitro)

		RAD51D	RAD51B
Description		RAD51 paralog D	RAD51 paralog B
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Replication Fork Cytoplasm Centrosome Rad51B-Rad51C-Rad51D-XRCC2 Complex	Nucleus Nucleoplasm Replication Fork Rad51B-Rad51C-Rad51D-XRCC2 Complex
	Molecular Function	Four-way Junction DNA Binding DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Gamma-tubulin Binding	Four-way Junction DNA Binding DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity
	Biological Process	Telomere Maintenance Double-strand Break Repair Via Homologous Recombination DNA Repair Reciprocal Meiotic Recombination Interstrand Cross-link Repair Strand Invasion Regulation Of Cell Cycle	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination Reciprocal Meiotic Recombination Blood Coagulation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Pathways		HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange TP53 Regulates Transcription of DNA Repair Genes	HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Advanced age-related macular degeneration ( 26691988) Adverse response to drug ( 30420678) Age-related macular degeneration ( 23455636) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Asthma ( 31361310 30929738 27182965 31619474) Asthma (childhood onset) ( 31036433 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 29059683) Breast cancer (male) ( 23001122) Cancer (pleiotropy) ( 27197191) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Granulocyte count ( 27863252) Heel bone mineral density ( 30598549) Height ( 31562340) Macular thickness ( 30535121) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 27863252) Medication use (thyroid preparations) ( 31015401) Monoclonal gammopathy of undetermined significance ( 30737484) Multiple sclerosis ( 31604244) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Nose size ( 27182965) Platelet count ( 27863252) Plateletcrit ( 27863252) Primary biliary cholangitis ( 26394269) Primary biliary cirrhosis ( 22961000) Prostate cancer ( 23535732) Red blood cell count ( 27863252) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systemic lupus erythematosus ( 26502338 28714469) Type 2 diabetes nephropathy ( 30566433) White blood cell count ( 27863252)
Interacting Genes		22 interacting genes: AMOTL2 BLM C1orf94 CCDC33 CEP57L1 EFHC2 IHO1 IKZF1 IKZF3 KIFC3 KRT15 LNX1 LZTS2 PRDM14 RAD51B RAD51C RHOU RNF138 SWSAP1 XRCC2 XRCC3 ZSWIM7	10 interacting genes: ABL1 FAM9B H1-0 H2BC8 H3C1 H4C14 RAD51 RAD51C RAD51D SWSAP1
Entrez ID		5892	5890
HPRD ID		04261	04255
Ensembl ID		ENSG00000185379	ENSG00000182185
Uniprot IDs		O75771	A0A024R656 C9JYJ0 O15315
PDB IDs		2KZ3
Enriched GO Terms of Interacting Partners?
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