RAD51 and ERCC2

  • Number of citations of the paper that reports this interaction (PubMedID 12359753)
  • 18
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

RAD51

ERCC2

Description RAD51 recombinase ERCC excision repair 2, TFIIH core complex helicase subunit
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anxiety and stress-related disorders ( 31116379)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Lung Cancer (DNA repair capacity) ( 23108145)
Interacting Genes 93 interacting genes: - ABL1 AGO2 ATM ATRX BARD1 BCCIP BCR BLM BRCA1 BRCA2 C1orf112 CASP3 CASP7 CCND1 CDH13 CHD3 CHEK1 CSNK2A1 CSNK2B CST6 CTCF DMC1 DNAJA3 ENAH EP400 ERCC2 ERCC5 EVL FANCD2 FANCI FBH1 FIGNL1 HID1 HNRNPC HSP90AA1 IL24 IRS1 ITIH5 MAPK8IP3 MDC1 MMS22L MND1 MSH4 NBN NCL NELFB NXF1 PALB2 PARPBP PCSK1N PDS5B PFN1 PLK1 POLA1 RAD18 RAD51AP1 RAD51AP2 RAD51B RAD51C RAD52 RAD54B RAD54L RECQL5 RELA RFWD3 RPA1 RPA2 RPA3 SEM1 SFR1 SIRT2 ST14 SUMO1 SUMO2 SWSAP1 TFF1 TP53 TP53BP1 UBE2I UCHL3 UGDH UHRF2 UMPS USP10 VASP VIM WDR48 WRN XPO1 XRCC2 XRCC3 ZDHHC17 16 interacting genes: AR CDK1 CDK7 ERCC3 ERCC5 GTF2H1 GTF2H2 GTF2H2C_2 GTF2H3 HERC5 MNAT1 MTDH RAD51 RAD52 TP53 TRIM25
Entrez ID 5888 2068
HPRD ID 01557 00530
Ensembl ID ENSG00000051180 ENSG00000104884
Uniprot IDs Q06609 P18074
PDB IDs 1B22 1N0W 5H1B 5H1C 5JZC 5NP7 5NWL 5IVW 5IY6 5IY7 5IY8 5IY9 5OF4 6NMI 6O9L 6O9M 6RO4
Enriched GO Terms of Interacting Partners?
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