RAD51 and CSNK2B

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		RAD51	CSNK2B
Description		RAD51 recombinase	casein kinase 2 beta
Image
GO Annotations	Cellular Component	Nuclear Chromosome Nuclear Chromosome, Telomeric Region Chromatin Nuclear Chromatin Condensed Chromosome Condensed Nuclear Chromosome Lateral Element Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Microtubule Organizing Center PML Body Protein-containing Complex Site Of Double-strand Break Perinuclear Region Of Cytoplasm	Chromatin Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cilium Protein Kinase CK2 Complex Nuclear Matrix PcG Protein Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Recombinase Activity Chromatin Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding Protein C-terminus Binding DNA-dependent ATPase Activity Single-stranded DNA-dependent ATP-dependent DNA Helicase Activity Enzyme Binding Identical Protein Binding DNA Polymerase Binding	Chromatin Binding Protein Serine/threonine Kinase Activity Signaling Receptor Binding Protein Binding Transcription Factor Binding Protein Kinase Regulator Activity Protein Domain Specific Binding Identical Protein Binding Ribonucleoprotein Complex Binding Metal Ion Binding
	Biological Process	Telomere Maintenance Via Recombination Double-strand Break Repair Via Homologous Recombination DNA Recombinase Assembly Regulation Of Protein Phosphorylation DNA Unwinding Involved In DNA Replication DNA Repair DNA Recombination Mitotic Recombination Cellular Response To DNA Damage Stimulus Reciprocal Meiotic Recombination Response To X-ray Response To Ionizing Radiation Regulation Of Double-strand Break Repair Via Homologous Recombination Telomere Maintenance Via Telomere Lengthening Replication Fork Processing Interstrand Cross-link Repair Strand Invasion Positive Regulation Of DNA Ligation Meiotic Cell Cycle Chromosome Organization Involved In Meiotic Cell Cycle Negative Regulation Of G0 To G1 Transition Cellular Response To Ionizing Radiation Cellular Response To Gamma Radiation Cellular Response To Hydroxyurea Cellular Response To Cisplatin Cellular Response To Camptothecin Response To Glucoside Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Mitotic Recombination-dependent Replication Fork Processing	Protein Folding Phosphatidylcholine Biosynthetic Process Signal Transduction Negative Regulation Of Cell Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Wnt Signaling Pathway Macroautophagy Peptidyl-threonine Phosphorylation Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Response To Testosterone Cellular Protein-containing Complex Assembly Neutrophil Degranulation Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Protein Kinase Activity Regulation Of DNA Binding Endothelial Tube Morphogenesis Liver Regeneration Regulation Of Signal Transduction By P53 Class Mediator
Pathways		HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange Transcriptional Regulation by E2F6 Meiotic recombination	Synthesis of PC WNT mediated activation of DVL Condensation of Prometaphase Chromosomes Signal transduction by L1 Neutrophil degranulation Regulation of TP53 Activity through Phosphorylation Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding Receptor Mediated Mitophagy RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN stability and activity
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester Amuvatinib	ATP Quercetin
Diseases
GWAS		Anxiety and stress-related disorders ( 31116379)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cutaneous lupus erythematosus ( 25827949) Inflammatory bowel disease ( 28067908) Systemic lupus erythematosus ( 26316170) Ulcerative colitis ( 28067908)
Interacting Genes		93 interacting genes: - ABL1 AGO2 ATM ATRX BARD1 BCCIP BCR BLM BRCA1 BRCA2 C1orf112 CASP3 CASP7 CCND1 CDH13 CHD3 CHEK1 CSNK2A1 CSNK2B CST6 CTCF DMC1 DNAJA3 ENAH EP400 ERCC2 ERCC5 EVL FANCD2 FANCI FBH1 FIGNL1 HID1 HNRNPC HSP90AA1 IL24 IRS1 ITIH5 MAPK8IP3 MDC1 MMS22L MND1 MSH4 NBN NCL NELFB NXF1 PALB2 PARPBP PCSK1N PDS5B PFN1 PLK1 POLA1 RAD18 RAD51AP1 RAD51AP2 RAD51B RAD51C RAD52 RAD54B RAD54L RECQL5 RELA RFWD3 RPA1 RPA2 RPA3 SEM1 SFR1 SIRT2 ST14 SUMO1 SUMO2 SWSAP1 TFF1 TP53 TP53BP1 UBE2I UCHL3 UGDH UHRF2 UMPS USP10 VASP VIM WDR48 WRN XPO1 XRCC2 XRCC3 ZDHHC17	204 interacting genes: ABHD4 ACTB ACTL6B ACTR1B ACTR5 ACVRL1 ADD1 ADH5 ANGPT2 ANKRD28 AP2M1 APLP1 ARAF ATF1 ATG101 ATXN3 BAG6 BCCIP BHLHE41 BID BMI1 BRCA1 BTF3 C6orf136 CACNA1A CALM1 CBX4 CCDC115 CCNH CD163 CD81 CDC25B CDC34 CDK1 CDK20 CDKN1A CENPB CHEK1 CHRNA4 CIC CIP2A CIPC CLOCK COIL COL4A2 COPS3 COPS7A CPNE7 CRISP2 CSN1S1 CSN2 CSNK1E CSNK2A1 CSNK2A2 CTDP1 CTNNB1 DACT1 DALRD3 DELEC1 DENND5A DNMT1 DPF3 EIF2S2 EIF5 EIF6 EPS8 ERCC8 ESR1 FAF1 FBXL15 FBXL5 FGB FGF1 FGF2 FIBP FKBP3 FTH1 GADD45GIP1 GAMT GBP2 GLB1 GNB5 GRK2 GSK3B GTPBP2 HEXB HIRIP3 HNRNPA2B1 HOXB6 HTRA1 IER3IP1 INTS11 IRS1 ITSN1 KCNA3 KDM6B KIF2C LCK LEPR LMO4 LRP5L LYN LYST MAPK14 MBD4 MDM2 MME MOXD1 MPP2 NAP1L1 NCF1 NMT2 NOLC1 NOTCH3 NPAS2 NRBP1 ODC1 OGA OGT PDS5A PER1 PER2 PFKFB4 PHC2 PHF11 PHRF1 PIN1 PITPNA PLXNA3 POT1 PPID PPP1CA PPP1CB PPP1CC PPP2CA PPP2R1A PPP2R1B PPP2R5D PPP2R5E PPP3CC PRKAB2 PRKCZ PRNP PROC PTPRK PYROXD2 RAD51 RFC1 RNF126 RNF7 RORB RPA1 RPL13 RPL41 RPL5 RPS6KA5 RPS6KB1 RPS6KB2 RRAD RXRA SARNP SDHA SEC11A SHANK3 SHMT1 SHMT2 SIMC1 SIRT1 SNX2 SPOUT1 SPSB3 SSB STAT5A STAU1 STK16 SUMO2 SYNE4 TCEAL7 TCTEX1D2 TFAP2A TLE1 TNFAIP1 TOP2B TP53 TP53BP2 TP63 TRIM27 TSEN54 TUBB2B UBE2I UPF1 USO1 UTP14A VDAC1 VRK3 WDR1 WDR18 WFIKKN1 ZFP36L1 ZNF44 ZNF71 ZNF76 ZNF784 ZNHIT1
Entrez ID		5888	1460
HPRD ID		01557	00278
Ensembl ID		ENSG00000051180	ENSG00000204435
Uniprot IDs		Q06609	A0A1U9X7J2 N0E4C7 P67870
PDB IDs		1B22 1N0W 5H1B 5H1C 5JZC 5NP7 5NWL	1DS5 1JWH 1QF8 3EED 4DGL 4MD7 4MD8 4MD9 4NH1 6Q38
Enriched GO Terms of Interacting Partners?
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