| Description |
protein tyrosine phosphatase receptor type M |
proprotein convertase subtilisin/kexin type 5 |
| Image |
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No pdb structure |
| GO Annotations |
Cellular Component |
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| Molecular Function |
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| Biological Process |
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| Pathways |
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| Drugs |
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| Diseases |
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| GWAS |
- Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
- Dialysis-related mortality ( 21546767)
- Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243)
- Glucose homeostasis traits ( 25524916)
- Hippocampal volume ( 29860282)
- Huntington's disease progression ( 28642124)
- Iris heterochromicity ( 30895295)
- Lateral ventricle temporal horn volume ( 31530798)
- Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828)
- Recurrence of mild malaria attacks ( 31667592)
- Response to methotrexate in rheumatoid arthritis ( 24583629)
- Sitting height ratio ( 25865494)
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- Alzheimer's disease progression score ( 29860282)
- Amyotrophic lateral sclerosis (age of onset) ( 22959728)
- Ankylosing spondylitis ( 30946743)
- Body fat distribution (leg fat ratio) ( 30664634)
- Body fat distribution (trunk fat ratio) ( 30664634)
- Diverticular disease ( 30177863)
- Glucocorticoid-induced osteonecrosis ( 26265699)
- Glucose homeostasis traits ( 25524916)
- Height ( 28552196 20881960 25282103 23563607 31562340)
- Inflammatory bowel disease ( 27569725)
- Intraocular pressure ( 29785010 31959993 30054594)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Lead levels ( 26025379)
- Male fertility ( 22633400)
- Metabolite levels (5-HIAA) ( 23319000)
- Pursuit maintenance gain ( 29064472)
- Response to fenofibrate (adiponectin levels) ( 23149075)
- Systemic sclerosis ( 30247649)
- Takayasu arteritis ( 25604533)
- Total ventricular volume (Alzheimer's disease interaction) ( 21116278)
- Vascular brain injury ( 25188341)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 25673412)
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| Interacting Genes |
11 interacting genes:
BCCIP
CDH1
CTNNB1
CTNND1
IQGAP1
PCSK5
PPFIBP1
PTPRA
PTPRK
PTPRS
RACK1
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19 interacting genes:
AMH
APPBP2
ATN1
CACNA1A
GLRX3
ITGA6
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP4-12
KRTAP5-9
LCE3C
MEOX2
NOTCH2NLA
NUFIP2
PMCH
PTPRM
REN
STK16
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| Entrez ID |
5797 |
5125 |
| HPRD ID |
01479 |
08985 |
| Ensembl ID |
ENSG00000173482
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ENSG00000099139
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| Uniprot IDs |
P28827
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Q92824
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| PDB IDs |
1RPM
2C9A
2V5Y
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| Enriched GO Terms of Interacting Partners? |
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| Tagcloud ? |
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| Tagcloud (Difference) ? |
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| Tagcloud (Intersection) ? |
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