PCSK5

Description proprotein convertase subtilisin/kexin type 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease progression score ( 29860282)
  • Amyotrophic lateral sclerosis (age of onset) ( 22959728)
  • Ankylosing spondylitis ( 30946743)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Diverticular disease ( 30177863)
  • Glucocorticoid-induced osteonecrosis ( 26265699)
  • Glucose homeostasis traits ( 25524916)
  • Height ( 28552196 20881960 25282103 23563607 31562340)
  • Inflammatory bowel disease ( 27569725)
  • Intraocular pressure ( 29785010 31959993 30054594)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Lead levels ( 26025379)
  • Male fertility ( 22633400)
  • Metabolite levels (5-HIAA) ( 23319000)
  • Pursuit maintenance gain ( 29064472)
  • Response to fenofibrate (adiponectin levels) ( 23149075)
  • Systemic sclerosis ( 30247649)
  • Takayasu arteritis ( 25604533)
  • Total ventricular volume (Alzheimer's disease interaction) ( 21116278)
  • Vascular brain injury ( 25188341)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412)
Interacting Genes 19 interacting genes: AMH APPBP2 ATN1 CACNA1A GLRX3 ITGA6 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP4-12 KRTAP5-9 LCE3C MEOX2 NOTCH2NLA NUFIP2 PMCH PTPRM REN STK16
Entrez ID 5125
HPRD ID 08985
Ensembl ID ENSG00000099139
Uniprot IDs Q92824
PDB IDs
Enriched GO Terms of Interacting Partners?
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