PTPN3 and ZAP70

  • Number of citations of the paper that reports this interaction (PubMedID 15588985)
  • 63
  • Data Source:
  • HPRD (in vitro)

PTPN3

ZAP70

Description protein tyrosine phosphatase non-receptor type 3 zeta chain of T cell receptor associated protein kinase 70
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Estimated glomerular filtration rate ( 31015462)
  • HIV-associated neurocognitive disorder ( 28447399)
  • HIV-associated neurocognitive disorder (asymptomatic neurocogntive impairment) ( 28447399)
  • HIV-associated neurocognitive disorder (mild neurocognitive disorder or asymptomatic neurocognitive impairment) ( 28447399)
  • Iris color (a* coordinate) ( 30895295)
  • Iris color (b* coordinate) ( 30895295)
  • Red blood cell density in sickle cell anemia ( 28552477)
  • Serum albumin level ( 29403010)
  • Staphylococcus aureus nasal carriage (persistent) ( 26569114)
Interacting Genes 18 interacting genes: ADAM17 AKR1C1 AKT1 CD247 DIP2A GHR HSPB1 LMO1 MAPK12 NXT2 RPS6KA1 VCP WDR6 YWHAB YWHAG YWHAQ ZAP70 ZCCHC10 62 interacting genes: ABL1 ACP1 ANAPC11 APP ASB3 CARD11 CBL CBLB CBLC CD247 CD3E CD5 CD79B CRK CSK DAPK1 DBNL DEF6 DUSP3 EGFR ERBB3 FCGR3A FCRL3 FYN GAB2 GRB2 IFNAR1 LAT LAX1 LCK LCP2 LRRK2 MUC1 NDUFB8 NFAM1 NR0B2 PAG1 PLCG1 PRLR PTK2B PTPN22 PTPN3 PTPN6 PTPRC RASA1 RNF41 SH2B3 SH3BP2 SHB SHC1 SIT1 SLA SLA2 SLAMF6 SOS1 TUBA1A TUBA4A TUBB TYROBP USP2 VAV1 WIPF1
Entrez ID 5774 7535
HPRD ID 06767 01495
Ensembl ID ENSG00000070159 ENSG00000115085
Uniprot IDs B7Z3V3 B7Z9V1 B7ZA03 P26045 Q8N4S3 P43403
PDB IDs 2B49 4QUM 4QUN 4RH5 4RH9 4RHG 4RI4 4RI5 4S0G 6HKS 1FBV 1M61 1U59 2CBL 2OQ1 2OZO 2Y1N 3ZNI 4A4B 4A4C 4K2R 4XZ0 4XZ1 5O76
Enriched GO Terms of Interacting Partners?
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