SPTBN4 and PTPRN

Number of citations of the paper that reports this interaction (PubMedID 11086001)
102

Data Source:
HPRD (two hybrid, in vivo)

		SPTBN4	PTPRN
Description		spectrin beta, non-erythrocytic 4	protein tyrosine phosphatase receptor type N
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Actin Filament Plasma Membrane Adherens Junction Spectrin Intercalated Disc Membrane Nuclear Matrix PML Body Node Of Ranvier Paranode Region Of Axon Neuronal Cell Body Axon Initial Segment Axon Hillock Extracellular Exosome Cell Body Fiber	Cell Nucleus Endosome Golgi Apparatus Plasma Membrane Synaptic Vesicle Integral Component Of Membrane Cell Junction Secretory Granule Transport Vesicle Membrane Neuronal Cell Body Perikaryon Axon Terminus Synapse
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Phospholipid Binding Phosphatase Binding Ankyrin Binding Spectrin Binding	Protein Tyrosine Phosphatase Activity Protein Binding Transcription Factor Binding Spectrin Binding Ubiquitin-like Protein Ligase Binding GTPase Binding
	Biological Process	MAPK Cascade Regulation Of Sodium Ion Transport ER To Golgi Vesicle-mediated Transport Cytoskeletal Anchoring At Plasma Membrane Axonogenesis Axon Guidance Sensory Perception Of Sound Adult Walking Behavior Fertilization Negative Regulation Of Heart Rate Vesicle-mediated Transport Transmission Of Nerve Impulse Central Nervous System Projection Neuron Axonogenesis Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Multicellular Organism Growth Clustering Of Voltage-gated Sodium Channels Actin Filament Capping Cardiac Conduction Protein Localization To Plasma Membrane	Response To Reactive Oxygen Species Luteinization Cytokine-mediated Signaling Pathway Insulin Secretion Response To Insulin Peptidyl-tyrosine Dephosphorylation Insulin Secretion Involved In Cellular Response To Glucose Stimulus Response To Estrogen Positive Regulation Of Transcription By RNA Polymerase II Response To CAMP Positive Regulation Of Type B Pancreatic Cell Proliferation Dense Core Granule Maturation
Pathways		NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport
Drugs
Diseases
GWAS		Antibody level in response to infection ( 25758998) Pulse pressure ( 30578418)	High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252)
Interacting Genes		14 interacting genes: ANK3 CDC37 CELSR3 CENPU CLK1 DISC1 GADD45A GSK3B NEK2 PFDN1 PTPRN PTPRN2 RPS6KA6 SPTAN1	13 interacting genes: CAPN2 CLN8 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 UBQLN4
Entrez ID		57731	5798
HPRD ID		09372	03466
Ensembl ID		ENSG00000160460	ENSG00000054356
Uniprot IDs		Q9H254	Q16849 Q96IA0
PDB IDs			2I1Y 2QT7 3N01 3N4W 3NG8 3NP5
Enriched GO Terms of Interacting Partners?
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