CALCOCO1 and CYTH3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CALCOCO1	CYTH3
Description		calcium binding and coiled-coil domain 1	cytohesin 3
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytosol Intracellular Membrane-bounded Organelle	Golgi Membrane Ruffle Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Nuclear Receptor Transcription Coactivator Activity Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Metal Ion Binding Armadillo Repeat Domain Binding	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Signal Transduction Positive Regulation Of Gene Expression Wnt Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Establishment Of Epithelial Cell Polarity
Pathways			Intra-Golgi traffic
Drugs			Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS		Panic disorder ( 19165232) Toenail selenium levels ( 25343990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
Interacting Genes		29 interacting genes: APP APTX ARNT CEP19 CREBBP CRYBA2 CTNNBL1 CWF19L2 CYTH3 DUSP13 EP300 FAM161A FOSL1 GABARAPL2 GRIK2 IPP ISOC1 KRT15 MAPK1 MYH6 NDC80 NEDD4 PCBD1 POLR2A SH3GL3 SMURF1 SRPK2 TBC1D15 TBC1D17	8 interacting genes: CALCOCO1 CNKSR1 CYTIP FRMD4B INAVA PIK3CA SYCE1 TAMALIN
Entrez ID		57658	9265
HPRD ID		13868	05469
Ensembl ID		ENSG00000012822	ENSG00000008256
Uniprot IDs		A0A024RAZ1 Q9P1Z2	O43739
PDB IDs			4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?
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