CALCOCO1 and DUSP13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CALCOCO1	DUSP13
Description		calcium binding and coiled-coil domain 1	dual specificity phosphatase 13
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Nuclear Receptor Transcription Coactivator Activity Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Metal Ion Binding Armadillo Repeat Domain Binding	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity
	Biological Process	Signal Transduction Positive Regulation Of Gene Expression Wnt Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Protein Dephosphorylation Spermatogenesis Dephosphorylation Peptidyl-tyrosine Dephosphorylation Meiotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Panic disorder ( 19165232) Toenail selenium levels ( 25343990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Blood protein levels ( 30072576 29875488) Body mass index ( 29273807) Height ( 31562340)
Interacting Genes		29 interacting genes: APP APTX ARNT CEP19 CREBBP CRYBA2 CTNNBL1 CWF19L2 CYTH3 DUSP13 EP300 FAM161A FOSL1 GABARAPL2 GRIK2 IPP ISOC1 KRT15 MAPK1 MYH6 NDC80 NEDD4 PCBD1 POLR2A SH3GL3 SMURF1 SRPK2 TBC1D15 TBC1D17	8 interacting genes: ACVR1 CALCOCO1 CARD9 CCDC85B HOOK2 LMNA SMURF1 TGFBR1
Entrez ID		57658	51207
HPRD ID		13868	13251
Ensembl ID		ENSG00000012822	ENSG00000079393
Uniprot IDs		A0A024RAZ1 Q9P1Z2	Q6B8I1 Q9UII6
PDB IDs			2GWO 2PQ5 5XJV
Enriched GO Terms of Interacting Partners?
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