CALCOCO1 and TBC1D17

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CALCOCO1	TBC1D17
Description		calcium binding and coiled-coil domain 1	TBC1 domain family member 17
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytosol Intracellular Membrane-bounded Organelle	Autophagosome Cytosol Recycling Endosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Nuclear Receptor Transcription Coactivator Activity Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Metal Ion Binding Armadillo Repeat Domain Binding	GTPase Activator Activity Protein Binding Rab GTPase Binding
	Biological Process	Signal Transduction Positive Regulation Of Gene Expression Wnt Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Intracellular Protein Transport Autophagy Retrograde Transport, Endosome To Golgi Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways			TBC/RABGAPs
Drugs
Diseases
GWAS		Panic disorder ( 19165232) Toenail selenium levels ( 25343990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		29 interacting genes: APP APTX ARNT CEP19 CREBBP CRYBA2 CTNNBL1 CWF19L2 CYTH3 DUSP13 EP300 FAM161A FOSL1 GABARAPL2 GRIK2 IPP ISOC1 KRT15 MAPK1 MYH6 NDC80 NEDD4 PCBD1 POLR2A SH3GL3 SMURF1 SRPK2 TBC1D15 TBC1D17	19 interacting genes: ASCC2 CALCOCO1 CCT5 CDKN2D DHX29 FBL GABARAPL1 GPS1 GTF3C1 MAP1LC3A MAP1LC3B NIPSNAP1 OPTN RAB1A RAB5A RAB5B RAB5C SLC1A5 TAX1BP1
Entrez ID		57658	79735
HPRD ID		13868	15471
Ensembl ID		ENSG00000012822	ENSG00000104946
Uniprot IDs		A0A024RAZ1 Q9P1Z2	Q9HA65
PDB IDs
Enriched GO Terms of Interacting Partners?
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