EP400 and TBC1D4

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EP400	TBC1D4
Description		E1A binding protein p400	TBC1 domain family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Swr1 Complex Nucleoplasm Nuclear Speck NuA4 Histone Acetyltransferase Complex	Cytosol Vesicle
	Molecular Function	DNA Binding Chromatin Binding Helicase Activity Protein Binding ATP Binding Protein Antigen Binding	GTPase Activator Activity Protein Binding Rab GTPase Binding
	Biological Process	Histone H4 Acetylation Histone H2A Acetylation	Intracellular Protein Transport Vesicle-mediated Transport Negative Regulation Of Vesicle Fusion Cellular Response To Insulin Stimulus Activation Of GTPase Activity
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF) DNA Damage/Telomere Stress Induced Senescence HATs acetylate histones	Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS		Body mass index ( 26426971) Red cell distribution width ( 27863252 28957414)	Diabetic retinopathy ( 23562823) Heart failure ( 20445134) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010 27863252) Mean platelet volume ( 27863252) Red blood cell count ( 29403010 27863252) Two-hour glucose ( 25043022) Type 2 diabetes ( 29926116) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		6 interacting genes: ALAS1 KAT5 MYC RAD51 TBC1D4 TRRAP	15 interacting genes: AKT1 CDK5RAP2 EP400 FBXW11 NAV1 NFAT5 PIN1 RBM12 RESF1 TASOR TET2 TOPBP1 U2SURP YWHAG ZMIZ1
Entrez ID		57634	9882
HPRD ID		09378	18164
Ensembl ID		ENSG00000183495	ENSG00000136111
Uniprot IDs		Q96L91	A0A3B3IRT3 O60343
PDB IDs			3QYB
Enriched GO Terms of Interacting Partners?
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