TBC1D4 and NAV1

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		TBC1D4	NAV1
Description		TBC1 domain family member 4	neuron navigator 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Vesicle	Cytoplasm Microtubule Microtubule Cytoskeleton Axon Initial Segment
	Molecular Function	GTPase Activator Activity Protein Binding Rab GTPase Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Negative Regulation Of Vesicle Fusion Cellular Response To Insulin Stimulus Activation Of GTPase Activity	Microtubule Bundle Formation Neuron Migration Nervous System Development
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS		Diabetic retinopathy ( 23562823) Heart failure ( 20445134) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010 27863252) Mean platelet volume ( 27863252) Red blood cell count ( 29403010 27863252) Two-hour glucose ( 25043022) Type 2 diabetes ( 29926116) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 26961502 25673413 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Celiac disease ( 23936387) Diastolic blood pressure ( 30578418) Heel bone mineral density ( 30598549) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Neurociticism ( 29500382) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Pulse pressure ( 27841878 30578418) Sleep duration (short sleep) ( 30846698) Waist circumference ( 25673412)
Interacting Genes		15 interacting genes: AKT1 CDK5RAP2 EP400 FBXW11 NAV1 NFAT5 PIN1 RBM12 RESF1 TASOR TET2 TOPBP1 U2SURP YWHAG ZMIZ1	7 interacting genes: APC APP GCC1 KIFAP3 KRT31 MAPRE1 TBC1D4
Entrez ID		9882	89796
HPRD ID		18164	10113
Ensembl ID		ENSG00000136111	ENSG00000134369
Uniprot IDs		A0A3B3IRT3 O60343	Q8NEY1
PDB IDs		3QYB
Enriched GO Terms of Interacting Partners?
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