PTEN and MAGI2

  • Number of citations of the paper that reports this interaction (PubMedID 10760291)
  • 102
  • Data Source:
  • HPRD (two hybrid, in vivo)

PTEN

MAGI2

Description phosphatase and tensin homolog membrane associated guanylate kinase, WW and PDZ domain containing 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 23007406)
  • Adverse response to drug ( 30420678)
  • Airway wall thickness ( 25517131)
  • Bitter beverage consumption ( 31046077)
  • Body mass index ( 28892062 25673413)
  • Bronchopulmonary dysplasia ( 23897914)
  • Chronotype ( 30696823)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • General risk tolerance (MTAG) ( 30643258)
  • Hippocampal atrophy ( 19668339)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • LDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Lead levels in blood ( 25820613)
  • Mammographic density (dense area) ( 25342443)
  • Memory dysfunction in frontotemporal lobe dementia ( 29724592)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Obesity-related traits ( 23251661)
  • Pursuit maintenance gain ( 29064472)
  • Response to anti-depressant treatment in major depressive disorder ( 22041458)
  • Schizophrenia ( 28991256 30285260)
  • Serum folate levels ( 29953918)
  • Visceral fat ( 30942860)
Interacting Genes 168 interacting genes: AATK AKAP12 AKT1 ANG ANXA2 AR ARF4 ATP5F1A ATP5F1C BCAR1 BEX1 CALM1 CAMK2G CAV1 CCND2 CDC27 CFL1 CHGB COPS6 CSNK1A1 CSNK2A1 CSNK2A2 CUL4B CXCL1 DAXX DBN1 DCAF11 DCAF13 DDB1 DLC1 DLG1 DNAJA1 DSP EEF2 EPHA2 ERBB3 ESR1 FASN FLNB GNAI1 GNAI2 GNB4 GPC4 GSTM2 H2AC4 HBA1 HSD17B1 HSP90AB1 HSPA8 HSPD1 IL24 INS ITPRID2 JUP KBTBD4 LATS1 LDHB LGALS1 LIMA1 LINC00839 MAGI2 MAGI3 MAP2K3 MAST1 MAST2 MAST3 MCRS1 METTL26 MME MPRIP MTHFD2 MVP MYC MYH10 MYL12A MYO1B MYO1C MYO1D MYOF NCF1 NDFIP1 NGB NME1 NUMB OSGIN1 OTUD3 PARK7 PBK PDGFRB PELO PKM PLEC PLK1 POLDIP2 PPL PPP1CA PRDX1 PSMD4 PTK2 PTK7 PXN RCC2 RPL10A RPL12 RPL13 RPL13A RPL14 RPL22L1 RPL23 RPL27 RPL27A RPL31 RPL38 RPL7 RPLP0 RPLP2 RPS13 RPS15A RPS17 RPS2 RPS20 RPS25 RPS26 RPS27 RPS27A RPS3 RPS4X RPS6 RPS9 S100A8 S100A9 SDC1 SDC4 SDCBP SETX SIRT4 SKP1 SLC25A3 SLC25A5 SLC9A3R1 SLC9A3R2 SNAI1 SNTB2 SNX27 SPTAN1 SPTBN1 SSR4 STK11 STUB1 TNKS TNKS2 TP53 TUBA1B TUBB TUBB4B TUFM TWIST1 TXN UBE2I UBE2L3 UBE2S USP13 USP7 UTP14A UTRN WWP2 YAP1 YES1 17 interacting genes: ACVR2A ADGRB1 ADRB1 ARRDC3 ATN1 CRHR1 CTNNB1 CTNND2 DLL1 DSCAML1 GRID2 PLXNB3 PTEN RAPGEF2 RPS6KA1 SMAD3 TGFA
Entrez ID 5728 9863
HPRD ID 03431 16212
Ensembl ID ENSG00000171862 ENSG00000187391
Uniprot IDs F6KD01 P60484 B7Z4H4 Q86UL8
PDB IDs 1D5R 2KYL 4O1V 5BUG 5BZX 5BZZ 1UEP 1UEQ 1UEW 1UJV 1WFV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?