MAGI2 and CTNND2

Number of citations of the paper that reports this interaction (PubMedID 10080919)
26

Data Source:
HPRD (in vivo, in vitro)

		MAGI2	CTNND2
Description		membrane associated guanylate kinase, WW and PDZ domain containing 2	catenin delta 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Late Endosome Plasma Membrane Cell-cell Junction Bicellular Tight Junction Postsynaptic Density Dendrite Protein-containing Complex Slit Diaphragm Synapse Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Postsynaptic Density Dendrite Perikaryon
	Molecular Function	Protein Binding Phosphatase Binding Receptor Signaling Complex Scaffold Activity Beta-1 Adrenergic Receptor Binding SMAD Binding Type II Activin Receptor Binding	Protein Binding Beta-catenin Binding Cadherin Binding
	Biological Process	Positive Regulation Of Receptor Internalization Planar Cell Polarity Pathway Involved In Axis Elongation Signal Transduction Negative Regulation Of Cell Proliferation Positive Regulation Of Signal Transduction Positive Regulation Of Neuron Projection Development Negative Regulation Of Cell Migration Positive Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Activin Receptor Signaling Pathway Nerve Growth Factor Signaling Pathway Receptor Clustering Protein Heterooligomerization Negative Regulation Of Protein Kinase B Signaling SMAD Protein Signal Transduction Mitotic Cell Cycle Arrest Glomerular Visceral Epithelial Cell Development Neuroligin Clustering Involved In Postsynaptic Membrane Assembly Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Synaptic Vesicle Clustering	Cell-cell Junction Assembly Cell Adhesion Signal Transduction Wnt Signaling Pathway Synapse Organization Regulation Of Canonical Wnt Signaling Pathway Dendritic Spine Morphogenesis Cell-cell Adhesion
Pathways		Nephrin family interactions
Drugs
Diseases			Cri du chat syndrome; Cat cry syndrome; Chromosme 5p deletion syndrome
GWAS		Acute lymphoblastic leukemia (childhood) ( 23007406) Adverse response to drug ( 30420678) Airway wall thickness ( 25517131) Bitter beverage consumption ( 31046077) Body mass index ( 28892062 25673413) Bronchopulmonary dysplasia ( 23897914) Chronotype ( 30696823) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) General risk tolerance (MTAG) ( 30643258) Hippocampal atrophy ( 19668339) Itch intensity from mosquito bite adjusted by bite size ( 28199695) LDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Lead levels in blood ( 25820613) Mammographic density (dense area) ( 25342443) Memory dysfunction in frontotemporal lobe dementia ( 29724592) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Pursuit maintenance gain ( 29064472) Response to anti-depressant treatment in major depressive disorder ( 22041458) Schizophrenia ( 28991256 30285260) Serum folate levels ( 29953918) Visceral fat ( 30942860)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Cannabis dependence symptom count ( 27028160) Cognitive performance (processing speed) ( 31598132) Common carotid intima-media thickness in HIV infection ( 29206233) Corneal astigmatism ( 30306274) Facial emotion recognition ( 28608620) Lewy body disease ( 25188341) Macular thickness ( 30535121) Myopia (pathological) ( 21095009) Pulse pressure ( 27841878) Response to antidepressants (symptom improvement) ( 29160301) Sensorimotor dexterity ( 31596458) Systolic blood pressure ( 27841878) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		17 interacting genes: ACVR2A ADGRB1 ADRB1 ARRDC3 ATN1 CRHR1 CTNNB1 CTNND2 DLL1 DSCAML1 GRID2 PLXNB3 PTEN RAPGEF2 RPS6KA1 SMAD3 TGFA	19 interacting genes: ABL1 ATN1 CDH1 CDH2 CLK1 CTNNB1 CTTN ERBIN FYN LCK LNX1 LRRC7 MAGI2 NUDT21 PDZD2 PSEN1 PSEN2 SPHK1 TTR
Entrez ID		9863	1501
HPRD ID		16212	09181
Ensembl ID		ENSG00000187391	ENSG00000169862
Uniprot IDs		B7Z4H4 Q86UL8	B4DJU1 B4DRK2 E7EPC8 Q9UQB3
PDB IDs		1UEP 1UEQ 1UEW 1UJV 1WFV
Enriched GO Terms of Interacting Partners?
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