RAB25 and RAB11FIP2

Number of citations of the paper that reports this interaction (PubMedID 11495908)
118

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		RAB25	RAB11FIP2
Description		RAB25, member RAS oncogene family	RAB11 family interacting protein 2
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GO Annotations	Cellular Component	Endosome Endomembrane System Pseudopodium Pseudopodium Membrane Cytoplasmic Vesicle Recycling Endosome Extracellular Exosome	Phagocytic Cup Cell Nucleoplasm Endosome Cytoplasmic Vesicle Membrane Cell Projection Intracellular Membrane-bounded Organelle Recycling Endosome Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Myosin V Binding	Protein Binding Rab GTPase Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Epithelial Cell Morphogenesis Intracellular Protein Transport Exocytosis Positive Regulation Of Cell Proliferation Positive Regulation Of Epithelial Cell Migration Pseudopodium Organization Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport	Renal Water Homeostasis Phagocytosis Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		RAB geranylgeranylation	Vasopressin regulates renal water homeostasis via Aquaporins
Drugs
Diseases
GWAS			Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		13 interacting genes: ACVR1 BMPR1B ITGB1 MED31 MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SMAD4 SMURF2 TGFBR1	14 interacting genes: AP2A1 CXCR2 EHD1 ITSN1 LRRK2 MARK2 MYO5B PDZD11 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 YWHAG
Entrez ID		57111	22841
HPRD ID		06698	10548
Ensembl ID		ENSG00000132698	ENSG00000107560
Uniprot IDs		P57735	Q7L804
PDB IDs		2OIL 3TSO	2GZD 2GZH 2K6S 3TSO 4C4P
Enriched GO Terms of Interacting Partners?
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